Evidence map›Paper›PMID 34948245›Full record

ArticleInternational journal of molecular sciences2021

Effects of Heme Oxygenase-1 on c-Kit-Positive Cardiac Cells.

Qianhong Li, Chandrashekhar Dasari, Ding Li, Asma Arshia, Ahmed Muaaz Umer, Mohamed Riad Abdelgawad Abouzid, Yiru Guo, Roberto Bolli

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Autophagy as a Guardian of Vascular Niche Homeostasis.International journal of molecular sciences · 2024
    Review
  4. Review
  5. Review
  6. The Vascular Niche for Adult Cardiac Progenitor Cells.Antioxidants (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Qianhong LiInstitute of Molecular Cardiology, Division of Cardiovascular Medicine, Department of Medicine, University of Louisville, Louisville, KY 40202, USA.
Chandrashekhar DasariInstitute of Molecular Cardiology, Division of Cardiovascular Medicine, Department of Medicine, University of Louisville, Louisville, KY 40202, USA.
Ding LiInstitute of Molecular Cardiology, Division of Cardiovascular Medicine, Department of Medicine, University of Louisville, Louisville, KY 40202, USA.
Asma ArshiaInstitute of Molecular Cardiology, Division of Cardiovascular Medicine, Department of Medicine, University of Louisville, Louisville, KY 40202, USA.
Ahmed Muaaz UmerInstitute of Molecular Cardiology, Division of Cardiovascular Medicine, Department of Medicine, University of Louisville, Louisville, KY 40202, USA.
Mohamed Riad Abdelgawad AbouzidInstitute of Molecular Cardiology, Division of Cardiovascular Medicine, Department of Medicine, University of Louisville, Louisville, KY 40202, USA.
Yiru GuoInstitute of Molecular Cardiology, Division of Cardiovascular Medicine, Department of Medicine, University of Louisville, Louisville, KY 40202, USA.
Roberto BolliInstitute of Molecular Cardiology, Division of Cardiovascular Medicine, Department of Medicine, University of Louisville, Louisville, KY 40202, USA.
University of Louisville · US

Funding

NIH HHS P01HL78825
6 · The paper itself

Abstract

Heme oxygenase-1 (HO-1) is one of the most powerful cytoprotective proteins known. The goal of this study was to explore the effects of HO-1 in c-kit-positive cardiac cells (CPCs). Lin

Indexed as

AnimalsAntioxidantsCell ProliferationDNA ReplicationGene ExpressionGene Expression RegulationHeartHeme Oxygenase-1Heme Oxygenase (Decyclizing)MaleMiceMice, Inbred C57BLMice, KnockoutMyocytes, CardiacNF-E2-Related Factor 2Proto-Oncogene Proteins c-kitAntioxidantsHeme Oxygenase-1Heme Oxygenase (Decyclizing)Nfe2l2 protein, mouseNF-E2-Related Factor 2Proto-Oncogene Proteins c-kitSuperoxide Dismutasec-kit-positive cardiac cellsDNA synthesisEc-SODheme oxygenase-1Nrf2

Identifiers

PMID34948245
PMCPMC8704354
OpenAlexW4200586462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.