Evidence map›Paper›PMID 34948210›Full record

ArticleInternational journal of molecular sciences2021

Effect of Mineral-Balanced Deep-Sea Water on Kidney Function and Renal Oxidative Stress Markers in Rats Fed a High-Salt Diet.

So Min Jo, Jain Nam, Soo-Yeon Park, Geonhee Park, Byeong Goo Kim, Gwi-Hwa Jeong, Byung Serk Hurh, Ji Yeon Kim

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Chronic kidney disease in Indonesia: evidence from a national health survey.Osong public health and research perspectives · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

So Min JoDepartment of Food Science and Technology, Seoul National University of Science and Technology, Seoul 01811, Korea.
Jain NamDepartment of Food Science and Technology, Seoul National University of Science and Technology, Seoul 01811, Korea.
Soo-Yeon ParkDepartment of Nano Bio Engineering, Seoul National University of Science and Technology, Seoul 01811, Korea.ORCID 0000-0003-0710-8316
Geonhee ParkSempio Fermentation Research Center, 183, Osongsaengmyeong 4-ro, Osong-eup, Heungdeok-gu, Cheongju-si 28156, Chungcheongbuk-do, Korea.
Byeong Goo KimSempio Fermentation Research Center, 183, Osongsaengmyeong 4-ro, Osong-eup, Heungdeok-gu, Cheongju-si 28156, Chungcheongbuk-do, Korea.
Gwi-Hwa JeongSempio Fermentation Research Center, 183, Osongsaengmyeong 4-ro, Osong-eup, Heungdeok-gu, Cheongju-si 28156, Chungcheongbuk-do, Korea.
Byung Serk HurhSempio Fermentation Research Center, 183, Osongsaengmyeong 4-ro, Osong-eup, Heungdeok-gu, Cheongju-si 28156, Chungcheongbuk-do, Korea.
Ji Yeon KimDepartment of Food Science and Technology, Seoul National University of Science and Technology, Seoul 01811, Korea.ORCID 0000-0002-4316-2726
Seoul National University of Science and Technology · KR

Funding

National Research Foundation of Korea No. 2017R1E1A1A01074320
6 · The paper itself

Abstract

This study investigated the effect of mineral-balanced deep-sea water (DSW) on kidney health using an animal model of kidney injury due to a high-sodium diet. High magnesium/low sodium (HMLS) and high magnesium/high calcium (HMHC) DSW samples with different mineral contents were prepared. Sprague-Dawley rats were fed an 8% sodium chloride (NaCl) diet for four weeks to induce kidney injury, and each group was supplied with purified water or mineral water. Kidney injury was observed in the NaCl group according to increased kidney injury markers and malondialdehydes, providing evidence of oxidative stress. However, the kidney injury was repaired by the intake of mineral-balanced DSW. It was confirmed that the HMLS and HMHC groups showed improved Na

Indexed as

AnimalsBiomarkersBlood PressureCalcium, DietaryDiet, Sodium-RestrictedKidneyMagnesiumMaleMineralsMineral WatersOxidative StressRatsRats, Sprague-DawleyReceptors, LDLSeawaterSodium Chloride, DietaryBiomarkersCalcium, DietaryMagnesiumMineralsMineral WatersReceptors, LDLSodium Chloride, Dietaryantioxidantcalciumdeep sea waterhigh-salt dietkidneykidney injurymagnesiumRNA-seqsodium excretion

Identifiers

PMID34948210
PMCPMC8705929
OpenAlexW4200164788

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.