Evidence map›Paper›PMID 34948207›Full record

ArticleInternational journal of molecular sciences2021

Decreased Podocyte Vesicle Transcytosis and Albuminuria in

Saaya Hatakeyama, Akihiro Tojo, Hiroshi Satonaka, Nami O Yamada, Takao Senda, Toshihiko Ishimitsu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Saaya HatakeyamaDepartment of Nephrology & Hypertension, Dokkyo Medical University, Tochigi 321-0293, Japan.
Akihiro TojoDepartment of Nephrology & Hypertension, Dokkyo Medical University, Tochigi 321-0293, Japan.
Hiroshi SatonakaDepartment of Nephrology & Hypertension, Dokkyo Medical University, Tochigi 321-0293, Japan.
Nami O YamadaDepartment of Anatomy, Gifu University, Gifu 501-1193, Japan.ORCID 0000-0002-1220-0814
Takao SendaDepartment of Anatomy, Gifu University, Gifu 501-1193, Japan.
Toshihiko IshimitsuDepartment of Nephrology & Hypertension, Dokkyo Medical University, Tochigi 321-0293, Japan.
Dokkyo Medical University · JPGifu University · JP

Funding

Dr. Naohiko Kobayashi, Kobayashi Clinic of Internal Medicine Research donation 2020-9
6 · The paper itself

Abstract

In minimal change nephrotic syndrome, podocyte vesicle transport is enhanced. Adenomatous polyposis coli (APC) anchors microtubules to cell membranes and plays an important role in vesicle transport. To clarify the role of APC in vesicle transport in podocytes, nephrotic syndrome was induced by puromycin amino nucleoside (PAN) injection in mice expressing APC1638T lacking the C-terminal of microtubule-binding site (APC1638T mouse); this was examined in renal tissue changes. The kidney size and glomerular area of APC1638T mice were reduced (

Indexed as

Adenomatous Polyposis ColiAlbuminuriaAnimalsDisease Models, AnimalKidney GlomerulusMaleMiceMice, Inbred C57BLNephrotic SyndromePodocytesPuromycinPuromycin AminonucleosideTranscytosisPuromycinPuromycin Aminonucleosideadenomatous polyposis coliglomerular filtration barriermicrotubulenephrotic syndromepodocytevesicle transport

Identifiers

PMID34948207
PMCPMC8708520
OpenAlexW4200505826

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.