Evidence map›Paper›PMID 34948159›Full record

ArticleInternational journal of molecular sciences2021

Uptake of Ozenoxacin and Other Quinolones in Gram-Positive Bacteria.

Yuly López, Laura Muñoz, Domingo Gargallo-Viola, Rafael Cantón, Jordi Vila, Ilonka Zsolt

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yuly LópezInstitute of Global Health of Barcelona, 08036 Barcelona, Spain.
Laura MuñozInstitute of Global Health of Barcelona, 08036 Barcelona, Spain.
Domingo Gargallo-ViolaABAC Therapeutics, 08950 Barcelona, Spain.
Rafael CantónDepartment of Clinical Microbiology, Hospital Universitario Ramón y Cajal & Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), 28034 Madrid, Spain.ORCID 0000-0003-1675-3173
Jordi VilaInstitute of Global Health of Barcelona, 08036 Barcelona, Spain.ORCID 0000-0002-8025-3926
Ilonka ZsoltFerrer International, 08029 Barcelona, Spain.ORCID 0000-0002-8900-722X
Barcelona Institute for Global Health · ESInstituto de Salud Carlos III · ESFerrer Grupo (Spain) · ES

Funding

Agency for Management of University and Research Grants of the Catalan Government SGR 0809Red Espanola de Investigacion en Patologia Infecciosa RD16/0016/0010Strategic Action on Health PI17/01468
6 · The paper itself

Abstract

The big problem of antimicrobial resistance is that it requires great efforts in the design of improved drugs which can quickly reach their target of action. Studies of antibiotic uptake and interaction with their target it is a key factor in this important challenge. We investigated the accumulation of ozenoxacin (OZN), moxifloxacin (MOX), levofloxacin (LVX), and ciprofloxacin (CIP) into the bacterial cells of 5 species, including

Indexed as

AminopyridinesQuinolonesTopoisomerase I InhibitorsBacterial ProteinsGram-Positive BacteriaAminopyridinesBacterial ProteinsozenoxacinQuinolonesTopoisomerase I Inhibitorsozenoxacinquinoloneuptake

Identifiers

PMID34948159
PMCPMC8708121
OpenAlexW4200222693

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.