Evidence map›Paper›PMID 34948098›Full record

ArticleInternational journal of molecular sciences2021

Long-Term Sex- and Genotype-Specific Effects of

Maren K Schroeder, Bin Liu, Robert G Hinshaw, Mi-Ae Park, Shuyan Wang, Shipra Dubey, Grace Geyu Liu, Qiaoqiao Shi, Peter Holton, Vladimir Reiser and 7 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
  5. Article
  6. Article
  7. Radiotherapy for non-cancer diseases: benefits and long-term risks.International journal of radiation biology · 2024
    Review
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Maren K SchroederDepartment of Neurology, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA 02115, USA.
Bin LiuDepartment of Neurology, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA 02115, USA.
Robert G HinshawDepartment of Neurology, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA 02115, USA.ORCID 0000-0003-0060-7753
Mi-Ae ParkDepartments of Radiology, Harvard Medical School, Boston, MA 02115, USA.
Shuyan WangDepartment of Radiology, Brigham and Women's Hospital, Boston, MA 02115, USA.
Shipra DubeyDepartments of Radiology, Harvard Medical School, Boston, MA 02115, USA.
Grace Geyu LiuDepartment of Neurology, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA 02115, USA.
Qiaoqiao ShiDepartment of Neurology, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA 02115, USA.
Peter HoltonDepartments of Radiology, Harvard Medical School, Boston, MA 02115, USA.
Vladimir ReiserGE Healthcare, Life Sciences, 101 Carnegie Center, Princeton, NJ 08540, USA.
Paul A JonesGE Healthcare, Pharmaceutical Diagnostics, Pollards Wood, Nightingales Lane, Chalfont St. Giles HP8 4SP, UK.ORCID 0000-0002-8385-1702
William TriggGE Healthcare, Pharmaceutical Diagnostics, Pollards Wood, Nightingales Lane, Chalfont St. Giles HP8 4SP, UK.ORCID 0000-0003-4046-0813
Marcelo F Di CarliDepartments of Radiology, Harvard Medical School, Boston, MA 02115, USA.
Barbara J CaldaroneMouse Behavioral Core, Harvard Medical School, Boston, MA 02115, USA.
Jacqueline P WilliamsDepartment of Environmental Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA.
M Kerry O'BanionDepartment of Neuroscience, Del Monte Neuroscience Institute, University of Rochester Medical Center, Rochester, NY 14642, USA.ORCID 0000-0003-1246-3363
Cynthia A LemereDepartment of Neurology, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA 02115, USA.ORCID 0000-0002-2983-7870
Brigham and Women's Hospital · USUniversity of Rochester Medical Center · USHarvard University · US

Funding

NASA 80NSSC18K0810NASA NNX14AI07G
6 · The paper itself

Abstract

Space radiation presents a substantial threat to travel beyond Earth. Relatively low doses of high-energy particle radiation cause physiological and behavioral impairments in rodents and may pose risks to human spaceflight. There is evidence that

Indexed as

Alzheimer DiseaseGamma RaysGenotypeIron RadioisotopesPresenilin-1Sex CharacteristicsAmyloid beta-Protein PrecursorAnimalsBehavior, AnimalFemaleMaleMiceMice, TransgenicSpatial MemoryTime FactorsAmyloid beta-Protein PrecursorAPP protein, mouseIron RadioisotopesPresenilin-1presenilin 1, mouse56Fe radiationAlzheimer’s diseasesex differences

Identifiers

PMID34948098
PMCPMC8703695
OpenAlexW4200120898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.