Evidence map›Paper›PMID 34948058›Full record

ArticleInternational journal of molecular sciences2021

Roles of the Na

Xiuju Li, Benjamin Buckley, Konstantin Stoletov, Yang Jing, Marie Ranson, John D Lewis, Mike Kelso, Larry Fliegel

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. The Remaining Conundrum of the Role of the NaReviews in cardiovascular medicine · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Xiuju LiDepartment of Biochemistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Benjamin BuckleyIllawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.ORCID 0000-0002-8346-3371
Konstantin StoletovDepartment of Oncology, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Yang JingDepartment of Biochemistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Marie RansonIllawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.ORCID 0000-0002-5570-9645
John D LewisDepartment of Oncology, University of Alberta, Edmonton, AB T6G 2H7, Canada.ORCID 0000-0002-7734-1204
Mike KelsoIllawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.ORCID 0000-0001-7809-6637
Larry FliegelDepartment of Biochemistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.ORCID 0000-0002-8946-4850
University of Alberta · CAUniversity of Wollongong · AU

Funding

Cancer Research Institute of Northern Alberta RES0050041National Science and Engineering Research Council for Canada RGPIN-2020-03932
6 · The paper itself

Abstract

Prostate cancer is a leading cause of cancer-associated deaths in men over 60 years of age. Most patients are killed by tumor metastasis. Recent evidence has implicated a role of the tumor microenvironment and urokinase plasminogen activator (uPA) in cancer cell migration, invasion, and metastasis. Here, we examine the role of the Na

Indexed as

Cell Line, TumorCell MovementCell ProliferationDisease ProgressionGene Expression Regulation, NeoplasticGene Knockout TechniquesHumansMaleMembrane ProteinsProstatic NeoplasmsSodium-Hydrogen Exchanger 1Tumor MicroenvironmentUp-RegulationMembrane ProteinsPLAU protein, humanSLC9A1 protein, humanSodium-Hydrogen Exchanger 1acid extrusionamiloridemetastasisNa+/H+ exchangerprostate cancerproton transporturokinase plasminogen activator

Identifiers

PMID34948058
PMCPMC8705693
OpenAlexW4200178441

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.