Evidence map›Paper›PMID 34948057›Full record

ArticleInternational journal of molecular sciences2021

Live-Cell Imaging of Single Neurotrophin Receptor Molecules on Human Neurons in Alzheimer's Disease.

Klaudia Barabás, Julianna Kobolák, Soma Godó, Tamás Kovács, Dávid Ernszt, Miklós Kecskés, Csaba Varga, Tibor Z Jánosi, Takahiro Fujiwara, Akihiro Kusumi and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Klaudia BarabásNAP Molecular Neuroendocrinology Research Group, Institute of Physiology, Medical School, Centre for Neuroscience, Szentágothai Research Institute, University of Pécs, 7624 Pécs, Hungary.
Julianna KobolákBioTalentum Ltd., 2100 Gödöllő, Hungary.ORCID 0000-0002-0986-9517
Soma GodóNAP Molecular Neuroendocrinology Research Group, Institute of Physiology, Medical School, Centre for Neuroscience, Szentágothai Research Institute, University of Pécs, 7624 Pécs, Hungary.
Tamás KovácsNAP Molecular Neuroendocrinology Research Group, Institute of Physiology, Medical School, Centre for Neuroscience, Szentágothai Research Institute, University of Pécs, 7624 Pécs, Hungary.
Dávid ErnsztNAP Molecular Neuroendocrinology Research Group, Institute of Physiology, Medical School, Centre for Neuroscience, Szentágothai Research Institute, University of Pécs, 7624 Pécs, Hungary.
Miklós KecskésNAP-B Cortical Microcircuits Research Group, Institute of Physiology, Medical School, Centre for Neuroscience, Szentágothai Research Institute, 7624 Pécs, Hungary.
Csaba VargaNAP-B Cortical Microcircuits Research Group, Institute of Physiology, Medical School, Centre for Neuroscience, Szentágothai Research Institute, 7624 Pécs, Hungary.
Tibor Z JánosiNAP Molecular Neuroendocrinology Research Group, Institute of Physiology, Medical School, Centre for Neuroscience, Szentágothai Research Institute, University of Pécs, 7624 Pécs, Hungary.
Takahiro FujiwaraInstitute for Integrated Cell-Material Sciences (WPI-iCeMS), Kyoto University, Kyoto 606-8501, Japan.
Akihiro KusumiMembrane Cooperativity Unit, Okinawa Institute of Science and Technology Graduate University (OIST), Onna 904-0495, Japan.
Annamária TéglásiBioTalentum Ltd., 2100 Gödöllő, Hungary.
András DinnyésBioTalentum Ltd., 2100 Gödöllő, Hungary.ORCID 0000-0003-3791-2583
István M ÁbrahámNAP Molecular Neuroendocrinology Research Group, Institute of Physiology, Medical School, Centre for Neuroscience, Szentágothai Research Institute, University of Pécs, 7624 Pécs, Hungary.
University of Pecs · HUBioTalentum (Hungary) · HUKyoto University · JPOkinawa Institute of Science and Technology Graduate University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurotrophin receptors such as the tropomyosin receptor kinase A receptor (TrkA) and the low-affinity binding p75 neurotrophin receptor p75

Indexed as

AdultAlzheimer DiseaseAnimalsCells, CulturedCell SurvivalFemaleHumansInduced Pluripotent Stem CellsMaleMiddle AgedMutationNerve Tissue ProteinsNeuronsPC12 CellsPresenilin-1RatsNerve Tissue ProteinsNGFR protein, humanNTRK1 protein, humanPresenilin-1PSEN1 protein, humanReceptors, Nerve Growth FactorReceptor, trkAAlzheimer’s diseasehuman-induced pluripotent stem celllive-cell single-molecule imagingneuronalp75NTRreceptor dynamicsTrkA

Identifiers

PMID34948057
PMCPMC8708879
OpenAlexW4200385205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.