Evidence map›Paper›PMID 34948048›Full record

ArticleInternational journal of molecular sciences2021

Interaction of KRSR Peptide with Titanium Dioxide Anatase (100) Surface: A Molecular Dynamics Simulation Study.

Tamás Tarjányi, Ferenc Bogár, Janos Minarovits, Márió Gajdács, Zsolt Tóth

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. KRSR and RGD Adsorption on TiOBiomolecules · 2026
    Article
  2. Osseointegration Process ImprovingCurrent topics in medicinal chemistry · 2025
    Review
  3. Article
  4. Peptides for Coating TiOInternational journal of molecular sciences · 2022
    Article
  5. Regenerative Medicine: Role of Stem Cells and Innovative Biomaterials 2.0.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Tamás TarjányiDepartment of Oral Biology and Experimental Dental Research, Faculty of Dentistry, University of Szeged, Tisza Lajos Körút 64-66, H-6720 Szeged, Hungary.ORCID 0000-0002-9481-5977
Ferenc BogárMTA-SZTE Biomimetic Systems Research Group, Eötvös Loránd Research Network (ELKH), Dóm tér 8, H-6720 Szeged, Hungary.ORCID 0000-0002-0611-1452
Janos MinarovitsDepartment of Oral Biology and Experimental Dental Research, Faculty of Dentistry, University of Szeged, Tisza Lajos Körút 64-66, H-6720 Szeged, Hungary.
Márió GajdácsDepartment of Oral Biology and Experimental Dental Research, Faculty of Dentistry, University of Szeged, Tisza Lajos Körút 64-66, H-6720 Szeged, Hungary.ORCID 0000-0003-1270-0365
Zsolt TóthDepartment of Experimental Physics, Faculty of Science and Informatics, University of Szeged, Dóm tér 9, H-6720 Szeged, Hungary.ORCID 0000-0003-1329-9470
University of Szeged · HUHungarian Research Network · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to its tensile strength and excellent biocompatibility, titanium (Ti) is commonly used as an implant material in medicine and dentistry. The success of dental implants depends on the formation of a contact between the oxidized surface of Ti implant and the surrounding bone tissue. The adsorption of proteins and peptides to the implant surface allows the bone-forming osteoblast cells to adhere to such modified surfaces. Recently, it has been observed that tetrapeptide KRSR (Lys-Arg-Ser-Arg) functionalization could promote osteoblast adhesion to implant surfaces. This may facilitate the establishment of an efficient bone-to implant contact and improve implant stability during the healing process. GROMACS, a molecular dynamics software package was used to perform a 200 ns simulation of adsorption of the KRSR peptide to the TiO

Indexed as

Models, MolecularMolecular ConformationMolecular Dynamics SimulationOligopeptidesTitaniumlysyl-arginyl-seryl-arginineOligopeptidesTitaniumtitanium dioxideKRSRosseointegrationpeptidePMFREMDtitanium dioxideumbrella sampling

Identifiers

PMID34948048
PMCPMC8707641
OpenAlexW4200046170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.