Evidence map›Paper›PMID 34948013›Full record

ArticleInternational journal of molecular sciences2021

The Protective Mechanism of Deuterated Linoleic Acid Involves the Activation of the Ca

Egor A Turovsky, Elena G Varlamova, Sergey V Gudkov, Egor Y Plotnikov

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 19 citations in OpenAlex.

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  12. Neuroprotection by Drugs, Nutraceuticals and Physical Activity.International journal of molecular sciences · 2023
    Article
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  17. Maresin-1 and Inflammatory Disease.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Egor A TurovskyFederal Research Center "Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences", Institute of Cell Biophysics of the Russian Academy of Sciences, 142290 Pushchino, Russia.ORCID 0000-0002-2528-8798
Elena G VarlamovaFederal Research Center "Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences", Institute of Cell Biophysics of the Russian Academy of Sciences, 142290 Pushchino, Russia.ORCID 0000-0003-1158-5174
Sergey V GudkovProkhorov General Physics Institute of the Russian Academy of Sciences, 38 Vavilove St., 119991 Moscow, Russia.ORCID 0000-0002-8814-6906
Egor Y PlotnikovA.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.ORCID 0000-0003-2838-3704
Institute of Cell Biophysics · RULomonosov Moscow State University · RUProkhorov General Physics Institute · RU

Funding

Russian Science Foundation 21-75-30009
6 · The paper itself

Abstract

Ischemia-like (oxygen-glucose deprivation, OGD) conditions followed by reoxygenation (OGD/R) cause massive death of cerebral cortex cells in culture as a result of the induction of necrosis and apoptosis. Cell death occurs as a result of an OGD-induced increase in Ca

Indexed as

AnimalsAstrocytesCalcium SignalingCells, CulturedCell SurvivalCytosolDeuteriumGene Expression RegulationHypoxia-Ischemia, BrainLinoleic AcidMiceModels, BiologicalReactive Oxygen SpeciesDeuteriumLinoleic AcidReactive Oxygen Speciesastrocytecell deathcell protectioncortexdeuterated linoleic polyunsaturated fatty acidoxygen-glucose deprivationROSsignaling

Identifiers

PMID34948013
PMCPMC8706680
OpenAlexW4200432797

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.