Evidence map›Paper›PMID 34947955›Full record

ArticleLife (Basel, Switzerland)2021

Posterior Circulation Endovascular Thrombectomy for Large Vessels Occlusion in Patients Presenting with NIHSS Score ≤ 10.

Andrea M Alexandre, Iacopo Valente, Arturo Consoli, Pietro Trombatore, Luca Scarcia, Mariangela Piano, Nicola Limbucci, Joseph Domenico Gabrieli, Riccardo Russo, Antonio Armando Caragliano and 13 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05708079 (Multidimensional Evaluation of Patients With Acute Ischemic Stroke Undergoing Pharmacological and Endovascular Revascularization Procedures for the Identification of Positive Prognostic Factors), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05708079 unknown statusnot on this map

Multidimensional Evaluation of Patients With Acute Ischemic Stroke Undergoing Pharmacological and Endovascular Revascularization Procedures for the Identification of Positive Prognostic Factors

Typeobservational_patient_registrySponsorFondazione Policlinico Universitario Agostino Gemelli IRCCSRan2020 to 2023Enrolled600ConditionsStroke, Endovascular Thrombectomy, Ischemic StrokeArmsEndovascular thrombectomy
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

  1. Impact of arterial occlusion location on early neurological deterioration in patients with minor stroke treated with intravenous thrombolysis. The MINORCAT-END study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 11 institutions in 4 countries.

Andrea M AlexandreUOC Radiologia e Neuroradiologia, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0002-8080-3916
Iacopo ValenteUOC Radiologia e Neuroradiologia, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0002-0451-2105
Arturo ConsoliDiagnostic and Interventional Neuroradiology, Foch Hospital, 92150 Suresnes, France.
Pietro TrombatoreUniversità Cattolica del Sacro Cuore, 00168 Rome, Italy.
Luca ScarciaUniversità Cattolica del Sacro Cuore, 00168 Rome, Italy.
Mariangela PianoNeuroradiologia, ASST Grande Ospedale Metropolitano Niguarda, 20162 Milano, Italy.
Nicola LimbucciUOC Interventistica Neurovascolare, A.O.U. Careggi, 54134 Firenze, Italy.
Joseph Domenico GabrieliNeuroradiology Unit, Policlinico Universitario di Padova, 35128 Padua, Italy.
Riccardo RussoDiagnostic and Interventional Neuroradiology, Foch Hospital, 92150 Suresnes, France.ORCID 0000-0002-9091-7394
Antonio Armando CaraglianoNeuroradiology Unit, Biomedical Sciences and of Morphologic and Functional Images, AOU Policlinico G. Martino, 98124 Messina, Italy.
Maria RuggieroNeuroradiology Unit, AUSL Romagna, 47521 Cesena, Italy.
Andrea SalettiInterventional Neuroradiology, S. Anna University Hospital of Ferrara, 44122 Ferrara, Italy.
Guido Andrea LazzarottiDepartment of Neuroradiology, Azienda Ospedaliero Universitaria Pisana (AOUP), 56126 Pisa, Italy.
Marco PileggiDepartment of Neuroradiology, Neurocenter of Southern Switzerland, 6900 Lugano, Switzerland.ORCID 0000-0002-7691-8999
Mirco CosottiniDepartment of Neuroradiology, Azienda Ospedaliero Universitaria Pisana (AOUP), 56126 Pisa, Italy.
Fabio PilatoNeurology, Neurophysiology and Neurobiology Unit, Department of Medicine, Università Campus Bio-Medico di Roma, 00128 Rome, Italy.ORCID 0000-0002-7248-3916
Artur SlomkaDepartment of Pathophysiology, Nicolaus Copernicus University in Torun, Ludwik Rydygier Collegium Medicum, 87-100 Torun, Poland.ORCID 0000-0002-4137-2981
Francesca ColòUniversità Cattolica del Sacro Cuore, 00168 Rome, Italy.
Francesca GiubboliniUniversità Cattolica del Sacro Cuore, 00168 Rome, Italy.
Giovanni FrisulloUniversità Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0002-1604-6594
Giacomo Della MarcaUniversità Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0001-6914-799X
Aldobrando BroccoliniUniversità Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0001-8295-9271
Alessandro PedicelliUOC Radiologia e Neuroradiologia, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Università Cattolica del Sacro Cuore · ITAgostino Gemelli University Polyclinic · ITAzienda Ospedaliera Universitaria Pisana · ITHôpital Foch · FRAzienda Ospedaliera Universitaria Policlinico "G. Martino" · ITAzienda Ospedaliero-Universitaria Careggi · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITLaboratory for Biomedical Neurosciences · CHNicolaus Copernicus University · PLUniversità Campus Bio-Medico · ITUniversity of Ferrara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mechanical thrombectomy (MT) is currently the gold standard treatment for ischemic stroke due to large vessel occlusion (LVO). However, the evidence of clinical usefulness of MT in posterior circulation LVO (pc-LVO) is still doubtful compared to the anterior circulation, especially in patients with mild neurological symptoms. The database of 10 high-volume stroke centers in Europe, including a period of three year and a half, was screened for patients with an acute basilar artery occlusion or a single dominant vertebral artery occlusion ("functional" BAO) presenting with a NIHSS ≤10, and with at least 3 months follow-up. A total of 63 patients were included. Multivariate analysis demonstrated that female gender (adjusted OR 0.04; 95% CI 0-0.84;

Indexed as

basilar arteryendovascular thrombectomylow NIHSSposterior circulation strokestroke

Identifiers

PMID34947955
PMCPMC8703711
OpenAlexW4200165170

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.