ArticleLife (Basel, Switzerland)2021
Isolation and Characterization of Bovine RVA from Northeast China, 2017-2020.
Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- Molecular epidemiology, seroprevalence and genetic characterization of bovine rotavirus in Qinghai yaks: first identification of G6P[5] genotype.Archives of virology · 2026Article
- A DPO-Enhanced Gold Nanoparticle-Assisted PCR Assay for Simultaneous Detection of Bovine Viral Diarrhea Virus, Astrovirus, and Rotavirus.Animals : an open access journal from MDPI · 2026Article
- Article
- Isolation, Identification, and Comprehensive Genomic Characterization of a Bovine Rotavirus G10P[11] Strain in China.Polish journal of microbiology · 2025Article
- Molecular Surveillance and Whole Genomic Characterization of Bovine Rotavirus A G6P[1] Reveals Interspecies Reassortment with Human and Feline Strains in China.Veterinary sciences · 2025Article
- Dairy Cattle Infection with Bovine Rotavirus at Different Growth Stages and Its Impact on Health and Productivity.Animals : an open access journal from MDPI · 2025Article
- Multiplex one-step RT-qPCR assays for simultaneous detection of BRV, BCoV,Frontiers in veterinary science · 2025Article
- Diagnosis of bovine rotavirus: an overview of currently available methods.Frontiers in microbiology · 2025Review
- Development and application of one-step multiplex Real-Time PCR for detection of three main pathogens associated with bovine neonatal diarrhea.Frontiers in cellular and infection microbiology · 2024Article
- Isolation and identification of BRV G6P[1] strain in Heilongjiang province, Northeast China.Frontiers in veterinary science · 2024Article
- Characterization of bovine rotavirus isolates from diarrheic calves in Türkiye.Molecular biology reports · 2023Article
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Authors and funding
14 authors at 3 institutions in 1 country.
Funding
Abstract
Group A rotaviruses (RVAs) are major enteric pathogens causing infections in calves. To investigate the epidemiological characteristics and genetic diversity of bovine rotavirus (BRV), 233 fecal samples were collected from calves with diarrhea in northeast China. The samples were analyzed for sequences encoding the inner capsid protein VP6 (subgroup) and the outer capsid proteins VP7 and VP4 (G and P type, respectively) using RT-PCR. Ten of the 233 samples (4.3%) were identified as BRV positive and were used for virus isolation and sequence analysis, revealing that all strains analyzed were of the G6P[1] genotype. The isolates exhibited high VP6 sequence identity to the USA cow RVA NCDV strain (>99% amino acid identity) and were further shown to be closely related to Japanese cow RVA BRV101 and Israelian human RVA G6P[1] strains, with >99% amino acid identity to VP7 and VP4 proteins, respectively. Comparative analyses of genome-predicted amino acid sequences between the isolates and the NCDV strains indicated that the antigenicity and infectivity of the strains isolated had changed. In this study, BRV genotypes and the genetic diversity among vaccinated cattle herds were monitored to provide epidemiological data and references for early diagnosis, allowing for early detection of new, potentially pathogenic RVA strains.
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