Evidence map›Paper›PMID 34947764›Full record

ArticleNanomaterials (Basel, Switzerland)2021

Single-Walled Carbon Nanotubes Inhibit TRPC4-Mediated Muscarinic Cation Current in Mouse Ileal Myocytes.

Lina T Al Kury, Dimitrios Papandreou, Vasyl V Hurmach, Dariia O Dryn, Mariia I Melnyk, Maxim O Platonov, Yuriy I Prylutskyy, Uwe Ritter, Peter Scharff, Alexander V Zholos

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. CHARMM-GUIJournal of chemical theory and computation · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Lina T Al KuryCollege of Natural and Health Sciences, Zayed University, Abu Dhabi 144534, United Arab Emirates.ORCID 0000-0002-8338-7655
Dimitrios PapandreouCollege of Natural and Health Sciences, Zayed University, Abu Dhabi 144534, United Arab Emirates.ORCID 0000-0002-4923-484X
Vasyl V HurmachESC "Institute of Biology and Medicine", Taras Shevchenko National University of Kyiv, 64 Volodymyrska Str., 01601 Kyiv, Ukraine.
Dariia O DrynESC "Institute of Biology and Medicine", Taras Shevchenko National University of Kyiv, 64 Volodymyrska Str., 01601 Kyiv, Ukraine.
Mariia I MelnykESC "Institute of Biology and Medicine", Taras Shevchenko National University of Kyiv, 64 Volodymyrska Str., 01601 Kyiv, Ukraine.
Maxim O PlatonovInstitute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, 150 Zabolotnogo Str., 03143 Kyiv, Ukraine.
Yuriy I PrylutskyyESC "Institute of Biology and Medicine", Taras Shevchenko National University of Kyiv, 64 Volodymyrska Str., 01601 Kyiv, Ukraine.
Uwe RitterInstitute of Chemistry and Biotechnology, Technical University of Ilmenau, 25 Weimarer Str., 98693 Ilmenau, Germany.ORCID 0000-0002-9315-4863
Peter ScharffInstitute of Chemistry and Biotechnology, Technical University of Ilmenau, 25 Weimarer Str., 98693 Ilmenau, Germany.
Alexander V ZholosESC "Institute of Biology and Medicine", Taras Shevchenko National University of Kyiv, 64 Volodymyrska Str., 01601 Kyiv, Ukraine.ORCID 0000-0002-4320-149X
National Academy of Sciences of Ukraine · UATaras Shevchenko National University of Kyiv · UATechnische Universität Ilmenau · DEZayed University · AE

Funding

the Ministry of Education and Science of Ukraine 19BF036-01
6 · The paper itself

Abstract

Single-walled carbon nanotubes (SWCNTs) are characterized by a combination of rather unique physical and chemical properties, which makes them interesting biocompatible nanostructured materials for various applications, including in the biomedical field. SWCNTs are not inert carriers of drug molecules, as they may interact with various biological macromolecules, including ion channels. To investigate the mechanisms of the inhibitory effects of SWCNTs on the muscarinic receptor cation current (mI

Indexed as

computer simulationgastrointestinal tractpatch clamp techniquesingle-walled carbon nanotubessmooth muscle cellTRPC4 channels

Identifiers

PMID34947764
PMCPMC8703819
OpenAlexW4200195985

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.