Evidence map›Paper›PMID 34947611›Full record

ArticleNanomaterials (Basel, Switzerland)2021

Biodistribution of Mesoporous Carbon Nanoparticles via Technetium-99m Radiolabelling after Oral Administration to Mice.

Maria Mamai, Dimitra Giasafaki, Evangelia-Alexandra Salvanou, Georgia Charalambopoulou, Theodore Steriotis, Penelope Bouziotis

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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  5. Review
  6. Nanoparticles for Bio-Medical Applications.Nanomaterials (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Maria MamaiInstitute of Nuclear & Radiological Sciences and Technology, Energy & Safety, National Centre for Scientific Research "Demokritos", 15341 Athens, Greece.
Dimitra GiasafakiInstitute of Nanoscience & Nanotechnology, National Centre for Scientific Research "Demokritos", 15341 Athens, Greece.
Evangelia-Alexandra SalvanouInstitute of Nuclear & Radiological Sciences and Technology, Energy & Safety, National Centre for Scientific Research "Demokritos", 15341 Athens, Greece.
Georgia CharalambopoulouInstitute of Nuclear & Radiological Sciences and Technology, Energy & Safety, National Centre for Scientific Research "Demokritos", 15341 Athens, Greece.ORCID 0000-0001-5236-1500
Theodore SteriotisInstitute of Nanoscience & Nanotechnology, National Centre for Scientific Research "Demokritos", 15341 Athens, Greece.ORCID 0000-0003-4978-7513
Penelope BouziotisInstitute of Nuclear & Radiological Sciences and Technology, Energy & Safety, National Centre for Scientific Research "Demokritos", 15341 Athens, Greece.ORCID 0000-0001-6778-2201
National Centre of Scientific Research "Demokritos" · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of ordered mesoporous matrices, and in particular carbon-based mesoporous nanoparticles has shown great potential towards enhancing the bioavailability of orally administered drugs. Nevertheless, elucidation of the in vivo absorption, distribution, and excretion of such carriers is essential for understanding their behaviour, and radiolabelling provides a very useful way to track their occurrence inside the body. In this work, uniform spherical CMK-1-type ordered mesoporous carbon nanoparticles have been radiolabelled with Technetium-99m (

Indexed as

biodegradationbiodistributionCMK-1mesoporous carbon nanoparticlesoral administrationradiolabellingTechnetium-99m

Identifiers

PMID34947611
PMCPMC8703805
OpenAlexW3217137419

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.