Evidence map›Paper›PMID 34947603›Full record

ArticleNanomaterials (Basel, Switzerland)2021

Gold Nanostars Embedded in PDMS Films: A Photothermal Material for Antibacterial Applications.

Gemma Toci, Francesca Olgiati, Piersandro Pallavicini, Yuri Antonio Diaz Fernandez, Lorenzo De Vita, Giacomo Dacarro, Pietro Grisoli, Angelo Taglietti

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gemma TociDepartment of Chemistry, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.
Francesca OlgiatiDepartment of Chemistry, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.
Piersandro PallaviciniDepartment of Chemistry, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.
Yuri Antonio Diaz FernandezDepartment of Chemistry, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0003-3422-8663
Lorenzo De VitaDepartment of Chemistry, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0001-8805-6102
Giacomo DacarroDepartment of Chemistry, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0002-8928-4972
Pietro GrisoliDepartment of Drug Sciences, University of Pavia, Viale Taramelli 14, 27100 Pavia, Italy.ORCID 0000-0003-2016-0135
Angelo TagliettiDepartment of Chemistry, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0003-0141-9201

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca PRIN 2017 project 2017EKCS35
6 · The paper itself

Abstract

Bacteria infections and related biofilms growth on surfaces of medical devices are a serious threat to human health. Controlled hyperthermia caused by photothermal effects can be used to kill bacteria and counteract biofilms formation. Embedding of plasmonic nano-objects like gold nanostars (GNS), able to give an intense photothermal effect when irradiated in the NIR, can be a smart way to functionalize a transparent and biocompatible material like polydimethylsiloxane (PDMS). This process enables bacteria destruction on surfaces of PDMS-made medical surfaces, an action which, in principle, can also be exploited in subcutaneous devices. We prepared stable and reproducible thin PDMS films containing controllable quantities of GNS, enabling a temperature increase that can reach more than 40 degrees. The hyperthermia exerted by this hybrid material generates an effective thermal microbicidal effect, killing bacteria with a near infrared (NIR) laser source with irradiance values that are safe for skin.

Indexed as

antibacterial materialsgold nanostarshyperthermiaPDMSphotothermal effect

Identifiers

PMID34947603
PMCPMC8707359

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.