Evidence map›Paper›PMID 34947551›Full record

ArticleNanomaterials (Basel, Switzerland)2021

Development and Characterization of pH-Dependent Cellulose Acetate Phthalate Nanofibers by Electrospinning Technique.

Gustavo Vidal-Romero, Virginia Rocha-Pérez, María L Zambrano-Zaragoza, Alicia Del Real, Lizbeth Martínez-Acevedo, Moisés J Galindo-Pérez, David Quintanar-Guerrero

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Gustavo Vidal-RomeroLaboratorio de Posgrado en Tecnología Farmacéutica, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de México, Cuautitlán Izcalli C.P. 54745, Estado de Mexico, Mexico.ORCID 0000-0002-2706-3429
Virginia Rocha-PérezDepartamento en Tecnología Farmacéutica, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México, Ciudad de Mexico C.P. 09230, Mexico.
María L Zambrano-ZaragozaLaboratorio de Procesos de Transformación y Tecnologías Emergentes de Alimentos, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de México, Cuautitlán Izcalli C.P. 54714, Estado de Mexico, Mexico.ORCID 0000-0003-0287-3772
Alicia Del RealDepartamento de Ingeniería Molecular de Materiales, Centro de Física Aplicada y Tecnología Avanzada, Universidad Nacional Autónoma de México, Campus Juriquilla, Santiago de Querétaro C.P. 76230, Querétaro, Mexico.ORCID 0000-0002-8647-5474
Lizbeth Martínez-AcevedoLaboratorio de Posgrado en Tecnología Farmacéutica, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de México, Cuautitlán Izcalli C.P. 54745, Estado de Mexico, Mexico.ORCID 0000-0001-6578-0886
Moisés J Galindo-PérezDepartamento en Tecnología Farmacéutica, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México, Ciudad de Mexico C.P. 09230, Mexico.ORCID 0000-0001-6413-9325
David Quintanar-GuerreroLaboratorio de Posgrado en Tecnología Farmacéutica, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de México, Cuautitlán Izcalli C.P. 54745, Estado de Mexico, Mexico.ORCID 0000-0002-0881-0943
Universidad de Cuautitlán Izcalli · MXUniversidad Nacional Autónoma de México · MXAutonomous University of Queretaro · MX

Funding

DGAPA-PAPIIT IN222420DGAPA-PAPIIT IN222520FESC-PIAPI 2040
6 · The paper itself

Abstract

The aim of this work was to obtain pH-dependent nanofibers with an electrospinning technique as a novel controlled release system for the treatment of periodontal disease (PD). Cellulose acetate phthalate (CAP) was selected as a pH-sensitive and antimicrobial polymer. The NF was optimized according to polymeric dispersion variables, polymer, and drug concentration, and characterized considering morphology, diameter, entrapment efficiency (EE), process efficiency (PE), thermal properties, and release profiles. Two solvent mixtures were tested, and CHX-CAP-NF prepared with acetone/ethanol at 12%

Indexed as

antimicrobial polymerchlorhexidinemorphologyperiodontal diseaserelease profile

Identifiers

PMID34947551
PMCPMC8706738
OpenAlexW3215567142

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.