ArticleMaterials (Basel, Switzerland)2021
Biocompatibility and Degradation Behavior of Molybdenum in an In Vivo Rat Model.
Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 54 citations in OpenAlex.
- Defining biomaterial-driven design principles for bioabsorbable flow diverters: current state and perspectives.Bioactive materials · 2027Review
- Biodegradable molybdenum intramedullary nails facilitate fracture repair through neutrophil-mediated immune response.Materials today. Bio · 2026Article
- Molybdenum as a biodegradable bone implant material assessed by ISO 10993-5/-12-compliant cytocompatibility testing and transcriptomic profiling in a human osteoblast cell line.Scientific reports · 2026Article
- Advancing Biomaterials Evaluation: A Human Quadruple Bone Cell Culture Reveals Molybdenum-Driven Pro-Osteogenic and Anti-osteoclastogenic Responses.ACS applied materials & interfaces · 2026Article
- TZM Mo alloy behaves superb as biodegradable metal for bone-fracture healing intramedullary nail implant.Materials today. Bio · 2026Article
- Magnesium ion implantation enhances the osseointegration and vascularization of 3D-Printed CoCrMo alloy scaffolds for load-bearing orthopedic applications.Bioactive materials · 2026Article
- Bioresorbable RFID capsule for assessing medication adherence.Nature communications · 2026Article
- Insights into the biological effects of molybdenum in an insect model (Frontiers in bioengineering and biotechnology · 2026Article
- Ultrafine Molybdenum Wire Braided Neurointerventional Implants: Bridging Biodegradability and Neurovascular Safety for Stroke Treatment.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Article
- Macrophage-related inflammatory responses to degradation products of biodegradable molybdenum implants.Materials today. Bio · 2025Article
- Overview of porous magnesium-based scaffolds: development, properties and biomedical applications.Materials futures · 2025Review
- Bioresorbable Materials for Wound Management.Biomimetics (Basel, Switzerland) · 2025Review
- Radiopaque FeMnN-Mo composite drawn filled tubing wires for braided absorbable neurovascular devices.Bioactive materials · 2024Article
- X-ray Microanalysis of Elemental Composition ofPlants (Basel, Switzerland) · 2024Article
- Resorbable Patient-Specific Implants of Molybdenum for Pediatric Craniofacial Surgery-Proof of Concept in an In Vivo Pilot Study.Journal of functional biomaterials · 2024Article
- A Predictive Toxicokinetic Model for Nickel Leaching from Vascular Stents.ACS biomaterials science & engineering · 2024Article
- Insights into the biocompatibility of biodegradable metallic molybdenum for cardiovascular applications-a critical review.Frontiers in bioengineering and biotechnology · 2024Review
- Uptake and Intracellular Fate of Fluorophore Labeled Metal-Organic-Framework (MOF) Nanoparticles.Environment & health (Washington, D.C.) · 2023Article
- Advances in Bioresorbable Triboelectric Nanogenerators.Chemical reviews · 2023Review
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
The biocompatibility and degradation behavior of pure molybdenum (Mo) as a bioresorbable metallic material (BMM) for implant applications were investigated. In vitro degradation of a commercially available Mo wire (ø250 µm) was examined after immersion in modified Kokubo's SBF for 28 days at 37 °C and pH 7.4. For assessment of in vivo degradation, the Mo wire was implanted into the abdominal aorta of female Wistar rats for 3, 6 and 12 months. Microstructure and corrosion behavior were analyzed by means of SEM/EDX analysis. After explantation, Mo levels in serum, urine, aortic vessel wall and organs were investigated via ICP-OES analysis. Furthermore, histological analyses of the liver, kidneys, spleen, brain and lungs were performed, as well as blood count and differentiation by FACS analysis. Levels of the C-reactive protein were measured in blood plasma of all the animals. In vitro and in vivo degradation behavior was very similar, with formation of uniform, non-passivating and dissolving product layers without occurrence of a localized corrosion attack. The in vitro degradation rate was 101.6 µg/(cm
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.