Evidence map›Paper›PMID 34947330›Full record

ArticleMaterials (Basel, Switzerland)2021

The Technological Process of Obtaining New Linen Dressings Did Not Cause the Loss of Their Wound-Healing Properties.

Tomasz Gębarowski, Izabela Jęśkowiak, Maciej Janeczek, Magdalena Żuk, Agnieszka Dobosz, Benita Wiatrak

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Investigation of the Properties of Linen Fibers and Dressings.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Tomasz GębarowskiDepartment of Medical Science Foundation, Wroclaw Medical University, Borowska 211, 50-560 Wroclaw, Poland.ORCID 0000-0002-8742-0790
Izabela JęśkowiakDepartment of Pharmacology, Wroclaw Medical University, Mikulicza-Radeckiego 2, 50-345 Wroclaw, Poland.ORCID 0000-0002-8829-4482
Maciej JaneczekDepartment of Biostructure and Animal Physiology, Wroclaw University of Environmental and Life Sciences, Kożuchowska 1/3, 51-631 Wroclaw, Poland.ORCID 0000-0003-4357-2271
Magdalena ŻukDepartment of Genetic Biochemistry, University of Wroclaw, Przybyszewskiego 63/77, 51-148 Wroclaw, Poland.ORCID 0000-0003-3343-9303
Agnieszka DoboszDepartment of Medical Science Foundation, Wroclaw Medical University, Borowska 211, 50-560 Wroclaw, Poland.
Benita WiatrakDepartment of Medical Science Foundation, Wroclaw Medical University, Borowska 211, 50-560 Wroclaw, Poland.ORCID 0000-0002-1404-2274
Wroclaw Medical University · PLWrocław University of Environmental and Life Sciences · PLUniversity of Wrocław · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLinen dressings were invented a few years ago but are still being worked on.

methodsThe obtained fabrics from the traditional variety of flax (Nike), two transgenic types of flax (M50 and B14) and the combination of these two flax fibers (M50 + B14) were tested in direct contact in cell cultures. Cell viability tests were performed, and the proliferation potential of cells on Balb3T3 and NHEK cell lines was checked using the Sulforhodamine-B (SRB) test. Moreover, the effect of new linen fabrics on apoptosis of THP-1 cells, as well as on the cell cycle of NHEK, HMCEV and THP-1, cells after 24 h of incubation was assessed.

resultsAll tested linen fabrics did not raise the number of necrotic cells. The tested fabrics caused a statistically significant decrease in the total protein content in skin cancer (except for 0.5 cm of Nike-type fabrics). The smallest cells in the apoptotic phase were in cultures treated with M50 fiber on an area of 0.5 cm. After 48 h of incubation of HEMVEC, NHEK and THP-1 cells with the tested fabrics, the growth of S-phase cells was noticed in all cases. At the same time, the greatest increase was observed with the use of B14 fabric. Necrosis is not statistically significant.

conclusionsAll the obtained flax fibers in the form of flax dressings did not lose their wound-healing properties under the influence of the technological process. New dressings made of genetically modified flax are a chance to increase the effectiveness of treatment of difficult healing wounds.

Indexed as

flax fabricshealing woundlinen dressings

Identifiers

PMID34947330
PMCPMC8707772
OpenAlexW4200270916

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.