Evidence map›Paper›PMID 34947280›Full record

ArticleMaterials (Basel, Switzerland)2021

Effect of a Nanostructured Titanium Surface on Gingival Cell Adhesion, Viability and Properties against

Khaled Mukaddam, Monika Astasov-Frauenhoffer, Elizaveta Fasler-Kan, Laurent Marot, Marcin Kisiel, Ernst Meyer, Joachim Köser, Marcus Waser, Michael M Bornstein, Sebastian Kühl

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  3. Copper doped hydroxyapatite nanocomposite thin films: synthesis, physico-chemical and biological evaluation.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
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  11. HowMaterials (Basel, Switzerland) · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Khaled MukaddamDepartment of Oral Surgery, University Center for Dental Medicine Basel (UZB), University of Basel, Mattenstrasse 40, 4058 Basel, Switzerland.ORCID 0000-0001-9137-1664
Monika Astasov-FrauenhofferDepartment Research, University Center for Dental Medicine Basel (UZB), University of Basel, Mattenstrasse 40, 4058 Basel, Switzerland.ORCID 0000-0001-9638-3939
Elizaveta Fasler-KanDepartment of Biomedicine, University of Basel and University Hospital Basel, Hebelstrasse 20, 4031 Basel, Switzerland.
Laurent MarotDepartment of Physics, University of Basel, Klingelbergstraße 82, 4056 Basel, Switzerland.ORCID 0000-0002-1529-9362
Marcin KisielDepartment of Physics, University of Basel, Klingelbergstraße 82, 4056 Basel, Switzerland.
Ernst MeyerDepartment of Physics, University of Basel, Klingelbergstraße 82, 4056 Basel, Switzerland.ORCID 0000-0001-6385-3412
Joachim KöserInstitut für Chemie und Bioanalytik, Hochschule für Life Sciences, Hofackerstrasse 30, 4132 Muttenz, Switzerland.ORCID 0000-0002-7569-6378
Marcus WaserInstitut für Chemie und Bioanalytik, Hochschule für Life Sciences, Hofackerstrasse 30, 4132 Muttenz, Switzerland.
Michael M BornsteinDepartment of Oral Health & Medicine, University Center for Dental Medicine Basel (UZB), University of Basel, Mattenstrasse 40, 4058 Basel, Switzerland.ORCID 0000-0002-7773-8957
Sebastian KühlDepartment of Oral Surgery, University Center for Dental Medicine Basel (UZB), University of Basel, Mattenstrasse 40, 4058 Basel, Switzerland.
University of Basel · CHUniversity of Bern · CH

Funding

ITI International Team for Implantology 1239_2017
6 · The paper itself

Abstract

objectivesThe transgingival part of titanium implants is either machined or polished. Cell-surface interactions as a result of nano-modified surfaces could help gingival fibroblast adhesion and support antibacterial properties by means of the physico-mechanical aspects of the surfaces. The aim of the present study was to determine how a nanocavity titanium surface affects the viability and adhesion of human gingival fibroblasts (HGF-1). Additionally, its properties against MATERIAL AND

methodsTwo different specimens were evaluated: commercially available machined titanium discs (MD) and nanostructured discs (ND). To obtain ND, machined titanium discs with a diameter of 15 mm were etched with a 1:1 mixture of 98% H

conclusionAntibacterial effects against CLINICAL RELEVANCE: Since osseointegration is well investigated, mucointegration is an important part of future research and developments. Little is known about how nanostructures on the machined transgingival part of an implant could possibly influence the surrounding tissue. Targeting titanium surfaces with improved antimicrobial properties requires extensive preclinical basic research to gain clinical relevance.

Indexed as

biocompatibilitycell viabilityimplant fabricationnanocavitysurface topography

Identifiers

PMID34947280
PMCPMC8706887
OpenAlexW4200168541

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.