ArticleMaterials (Basel, Switzerland)2021
Influence of Natural Polysaccharides on Properties of the Biomicroconcrete-Type Bioceramics.
Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- The Synergistic Effect of Polysaccharides and Silane Coupling Agents on the Properties of Calcium Phosphate-Based Bone Substitutes.International journal of molecular sciences · 2025Article
- Bacterial-Derived Polyhydroxyalkanoate/Bioceramic Composites in Clinical Practice: State of the Art and Future Perspectives.ACS biomaterials science & engineering · 2025Review
- Polysaccharide Hydroxyapatite (Nano)composites and Their Biomedical Applications: An Overview of Recent Years.ACS omega · 2024Review
- The Influence of Citrus Pectin and Polyacrylamide Modified with Plant-Derived Additives on the Properties of α-TCP-Based Bone Cements.Polymers · 2024Article
- Physicochemical Properties of Inorganic and Hybrid Hydroxyapatite-Based Granules Modified with Citric Acid or Polyethylene Glycol.Molecules (Basel, Switzerland) · 2024Article
- The influence of silane coupling agents on the properties of α-TCP-based ceramic bone substitutes for orthopaedic applications.RSC advances · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
In this paper, novel hybrid biomicroconcrete-type composites were developed and investigated. The solid phase of materials consisted of a highly reactive α -tricalcium phosphate (α-TCP) powder, hybrid hydroxyapatite-chitosan (HAp-CTS) material in the form of powder and granules (as aggregates), and the polysaccharides sodium alginate (SA) or hydroxypropyl methylcellulose (HPMC). The liquid/gel phase in the studied materials constituted a citrus pectin gel. The influence of SA or HPMC on the setting reaction, microstructure, mechanical as well as biological properties of biomicroconcretes was investigated. Studies revealed that manufactured cement pastes were characterized by high plasticity and cohesion. The dual setting system of developed biomicroconcretes, achieved through α-TCP setting reaction and polymer crosslinking, resulted in a higher compressive strength. Material with the highest content of sodium alginate possessed the highest mechanical strength (~17 MPa), whereas the addition of hydroxypropyl methylcellulose led to a subtle compressive strength decrease. The obtained biomicroconcretes were chemically stable and characterized by a high bioactive potential. The novel biomaterials with favorable physicochemical and biological properties can be prosperous materials for filling bone tissue defects of any shape and size.
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Registered trials
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