Evidence map›Paper›PMID 34946992›Full record

ArticleJournal of fungi (Basel, Switzerland)2021

Chitin Deacetylase, a Novel Target for the Design of Agricultural Fungicides.

Jesús M Martínez-Cruz, Álvaro Polonio, Riccardo Zanni, Diego Romero, Jorge Gálvez, Dolores Fernández-Ortuño, Alejandro Pérez-García

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Plant signaling & behavior · 2025
    Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jesús M Martínez-CruzDepartamento de Microbiología, Facultad de Ciencias, Universidad de Málaga, 29071 Málaga, Spain.ORCID 0000-0002-3632-0837
Álvaro PolonioDepartamento de Microbiología, Facultad de Ciencias, Universidad de Málaga, 29071 Málaga, Spain.
Riccardo ZanniMolecular Topology and Drug Design Unit, Department of Physical Chemistry, University of Valencia, 46010 Valencia, Spain.ORCID 0000-0002-3388-3730
Diego RomeroDepartamento de Microbiología, Facultad de Ciencias, Universidad de Málaga, 29071 Málaga, Spain.ORCID 0000-0002-2052-6515
Jorge GálvezMolecular Topology and Drug Design Unit, Department of Physical Chemistry, University of Valencia, 46010 Valencia, Spain.ORCID 0000-0003-0928-8437
Dolores Fernández-OrtuñoDepartamento de Microbiología, Facultad de Ciencias, Universidad de Málaga, 29071 Málaga, Spain.ORCID 0000-0002-3134-3095
Alejandro Pérez-GarcíaDepartamento de Microbiología, Facultad de Ciencias, Universidad de Málaga, 29071 Málaga, Spain.ORCID 0000-0002-1065-0360
Consejo Superior de Investigaciones Científicas · ESUniversitat de València · ES

Funding

Agencia Estatal de Investigación AGL2016-76216-C2-1-R, AGL2016-76216-C2-2-R, PID2019-107464RB-C2
6 · The paper itself

Abstract

Fungicide resistance is a serious problem for agriculture. This is particularly apparent in the case of powdery mildew fungi. Therefore, there is an urgent need to develop new agrochemicals. Chitin is a well-known elicitor of plant immunity, and fungal pathogens have evolved strategies to overcome its detection. Among these strategies, chitin deacetylase (CDA) is responsible for modifying immunogenic chitooligomers and hydrolysing the acetamido group in the N-acetylglucosamine units to avoid recognition. In this work, we tested the hypothesis that CDA can be an appropriate target for antifungals using the cucurbit powdery mildew pathogen

Indexed as

chitinchitin deacetylasechitin-triggered immunityEDTAPodosphaera xanthiipowdery mildewsRNAi silencing

Identifiers

PMID34946992
PMCPMC8706340
OpenAlexW3217034523

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.