Evidence map›Paper›PMID 34946979›Full record

ArticleGenes2021

Clinical Theragnostic Relationship between Chemotherapeutic Resistance, and Sensitivity and miRNA Expressions in Head and Neck Cancers: A Systematic Review and Meta-Analysis Protocol.

Peter Shaw, Greg Raymond, Raghul Senthilnathan, Chellan Kumarasamy, Siddhartha Baxi, Deepa Suresh, Sameep Shetty, Ravishankar Ram M, Harish C Chandramoorthy, Palanisamy Sivanandy and 4 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Non-coding RNA and drug resistance in head and neck cancer.Cancer drug resistance (Alhambra, Calif.) · 2024
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 12 institutions in 6 countries.

Peter ShawDepartment of Artificial Intelligence, Nanjing University of Information Science and Technology (NUIST), Nanjing 210044, China.ORCID 0000-0002-3187-8938
Greg RaymondNorthern Territory Medical Program, CDU Campus, Flinders University, Ellengowan Drive, Darwin, NT 0909, Australia.
Raghul SenthilnathanSchool of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore 632014, India.ORCID 0000-0002-0779-809X
Chellan KumarasamyKumarasamy School of Health and Medical Sciences, Curtin University, Perth, WA 6102, Australia.
Siddhartha BaxiMBBS, FRANZCR GAICD (SB), Genesis Care Gold Coast Radiation Oncologist, Southport, QLD 4224, Australia.
Deepa SureshDivision of Endocrinology, Department of Internal Medicine, Mayo Clinic Florida, Jacksonville, FL 32224, USA.
Sameep ShettyDepartment of Oral and Maxillofacial Surgery, Manipal College of Dental Sciences, Mangalore, Academy of Higher Education, A Constituent of MAHE, Manipal 576104, India.ORCID 0000-0001-8729-9348
Ravishankar Ram MDepartment of Pharmaceutical Biology, Faculty of Pharmaceutical Sciences, UCSI University Kuala Lumpur (South Wing), No.1, Jalan Menara Gading, UCSI Heights 56000 Cheras, Kuala Lumpur 57000, Malaysia.ORCID 0000-0003-4229-5778
Harish C ChandramoorthyDepartment of Microbiology and Clinical Parasitology, College of Medicine, King Khalid University, Abha 61421, Saudi Arabia.
Palanisamy SivanandyDepartment of Pharmacy Practice, School of Pharmacy, International Medical University, Bukit Jalil, Kuala Lumpur 57000, Malaysia.ORCID 0000-0002-9183-5091
Suja SamiappanDepartment of Biochemistry, Bharathiar University, Coimbatore 641046, India.
Mogana RajagopalDepartment of Pharmaceutical Biology, Faculty of Pharmaceutical Sciences, UCSI University Kuala Lumpur (South Wing), No.1, Jalan Menara Gading, UCSI Heights 56000 Cheras, Kuala Lumpur 57000, Malaysia.ORCID 0000-0002-5664-9293
Sunil KrishnanDepartment of Radiation Oncology, Mayo Clinic Florida, 4500 San Pablo Road S., Jacksonville, FL 32224, USA.
Rama JayarajNorthern Territory Institute of Research and Training, Darwin, NT 0909, Australia.ORCID 0000-0002-2179-0510
Mayo Clinic in Florida · USUCSI University · MYBharathiar University · INCurtin University · AUFlinders University · AUGold Coast Health · AUIMU University · MYKing Khalid University · SAManipal Academy of Higher Education · INNanjing University of Information Science and Technology · CNNorthern Territory Health Services · AUVellore Institute of Technology University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug Resistance, NeoplasmHead and Neck NeoplasmsMicroRNAsBiomarkers, TumorGene Expression Regulation, NeoplasticHumansMeta-Analysis as TopicPrognosisSurvival RateSystematic Reviews as TopicBiomarkers, TumorMicroRNAschemoresistancedown-regulationhazard ratiohead and neck cancermiRNApatient survivalprotocolsystematic reviewup-regulation

Identifiers

PMID34946979
PMCPMC8702026
OpenAlexW4200603306

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.