Evidence map›Paper›PMID 34946968›Full record

ArticleGenes2021

Gene Amplification as a Mechanism of Yeast Adaptation to Nonsense Mutations in Release Factor Genes.

Evgeniia M Maksiutenko, Yury A Barbitoff, Andrew G Matveenko, Svetlana E Moskalenko, Galina A Zhouravleva

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Prion-Dependent Lethality ofInternational journal of molecular sciences · 2025
    Article
  2. Antibiotic resistance mediated by gene amplifications.npj antimicrobials and resistance · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Evgeniia M MaksiutenkoDepartment of Genetics and Biotechnology, St. Petersburg State University, 199034 St. Petersburg, Russia.ORCID 0000-0002-6896-8232
Yury A BarbitoffDepartment of Genetics and Biotechnology, St. Petersburg State University, 199034 St. Petersburg, Russia.ORCID 0000-0002-3222-440X
Andrew G MatveenkoDepartment of Genetics and Biotechnology, St. Petersburg State University, 199034 St. Petersburg, Russia.ORCID 0000-0002-9458-0194
Svetlana E MoskalenkoDepartment of Genetics and Biotechnology, St. Petersburg State University, 199034 St. Petersburg, Russia.ORCID 0000-0003-0419-0000
Galina A ZhouravlevaDepartment of Genetics and Biotechnology, St. Petersburg State University, 199034 St. Petersburg, Russia.ORCID 0000-0002-3013-4662
St Petersburg University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein synthesis (translation) is one of the fundamental processes occurring in the cells of living organisms. Translation can be divided into three key steps: initiation, elongation, and termination. In the yeast

Indexed as

Gene AmplificationAdaptation, PhysiologicalChromosomes, FungalCodon, NonsensePeptide Termination FactorsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsWhole Genome SequencingCodon, NonsensePeptide Termination FactorsSaccharomyces cerevisiae ProteinsSUP35 protein, S cerevisiaeSUP45 protein, S cerevisiaeamplificationchromosome instabilityeRF1eRF3nonsense suppressionplasmid copy numberrelease factorstranslation terminationWGSyeast

Identifiers

PMID34946968
PMCPMC8701342
OpenAlexW4200315221

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.