Evidence map›Paper›PMID 34946961›Full record

ArticleGenes2021

Polymorphisms in Genes Involved in Osteoblast Differentiation and Function Are Associated with Anthropometric Phenotypes in Spanish Women.

Clara Pertusa, Sofía P Ruzo, Layla Panach, Damián Mifsut, Juan J Tarín, Antonio Cano, Miguel Ángel García-Pérez

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Clara PertusaResearch Unit, INCLIVA Health Research Institute, 46010 Valencia, Spain.
Sofía P RuzoResearch Unit, INCLIVA Health Research Institute, 46010 Valencia, Spain.
Layla PanachResearch Unit, INCLIVA Health Research Institute, 46010 Valencia, Spain.
Damián MifsutOrthopedic Surgery and Traumatology, Clinic Hospital, INCLIVA Institute of Health Research, 46010 Valencia, Spain.ORCID 0000-0003-1852-8439
Juan J TarínDepartment of Cellular Biology, Functional Biology and Physical Anthropology, University of Valencia, 46100 Burjassot, Spain.
Antonio CanoDepartment of Pediatrics, Obstetrics and Gynecology, University of Valencia, 46010 Valencia, Spain.ORCID 0000-0001-8046-0303
Miguel Ángel García-PérezResearch Unit, INCLIVA Health Research Institute, 46010 Valencia, Spain.ORCID 0000-0002-0626-7502
INCLIVA Health Research Institute · ESUniversitat de València · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Much of the genetic variance associated with osteoporosis is still unknown. Bone mineral density (BMD) is the main predictor of osteoporosis risk, although other anthropometric phenotypes have recently gained importance. The aim of this study was to analyze the association of SNPs in genes involved in osteoblast differentiation and function with BMD, body mass index (BMI), and waist (WC) and hip (HC) circumferences. Four genes that affect osteoblast differentiation and/or function were selected from among the differentially expressed genes in fragility hip fracture (

Indexed as

Polymorphism, Single NucleotideAbsorptiometry, PhotonAgedAllelic ImbalanceBasic Helix-Loop-Helix Proteinsbeta CateninBody Mass IndexBone DensityCell DifferentiationCohort StudiesFemaleForkhead Transcription FactorsGenetic Association StudiesHumansMEF2 Transcription FactorsMiddle AgedBasic Helix-Loop-Helix Proteinsbeta CateninCTNNB1 protein, humanEBF2 protein, humanForkhead Transcription FactorsFOXC1 protein, humanMEF2C protein, humanMEF2 Transcription FactorsBMDBMICTNNB1 and MEF2C genesosteoporosiswomen

Identifiers

PMID34946961
PMCPMC8701034
OpenAlexW4200321514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.