Evidence map›Paper›PMID 34946930›Full record

ArticleGenes2021

Genotype-Specific Lesion Growth Rates in Stargardt Disease.

Rachael C Heath Jeffery, Jennifer A Thompson, Johnny Lo, Tina M Lamey, Terri L McLaren, Ian L McAllister, Ian J Constable, John N De Roach, Fred K Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Stargardt macular dystrophy and therapeutic approaches.The British journal of ophthalmology · 2024
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Rachael C Heath JefferyCentre for Ophthalmology and Visual Science (Incorporating Lions Eye Institute), The University of Western Australia, Nedlands, WA 6009, Australia.
Jennifer A ThompsonAustralian Inherited Retinal Disease Registry and DNA Bank, Department of Medical Technology and Physics, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia.ORCID 0000-0003-3553-6457
Johnny LoSchool of Science, Edith Cowan University, Joondalup, WA 6027, Australia.ORCID 0000-0003-1913-5354
Tina M LameyCentre for Ophthalmology and Visual Science (Incorporating Lions Eye Institute), The University of Western Australia, Nedlands, WA 6009, Australia.
Terri L McLarenCentre for Ophthalmology and Visual Science (Incorporating Lions Eye Institute), The University of Western Australia, Nedlands, WA 6009, Australia.
Ian L McAllisterCentre for Ophthalmology and Visual Science (Incorporating Lions Eye Institute), The University of Western Australia, Nedlands, WA 6009, Australia.ORCID 0000-0003-3262-0821
Ian J ConstableCentre for Ophthalmology and Visual Science (Incorporating Lions Eye Institute), The University of Western Australia, Nedlands, WA 6009, Australia.
John N De RoachCentre for Ophthalmology and Visual Science (Incorporating Lions Eye Institute), The University of Western Australia, Nedlands, WA 6009, Australia.
Fred K ChenCentre for Ophthalmology and Visual Science (Incorporating Lions Eye Institute), The University of Western Australia, Nedlands, WA 6009, Australia.ORCID 0000-0003-2809-9930
Lions Eye Institute · AUEdith Cowan University · AUSir Charles Gairdner Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reported growth rates (GR) of atrophic lesions in Stargardt disease (STGD1) vary widely. In the present study, we report the longitudinal natural history of patients with confirmed biallelic

Indexed as

AdultAgedAged, 80 and overATP-Binding Cassette TransportersFemaleFluorescein AngiographyGenotypeHumansMacular DegenerationMaleMiddle AgedOptical ImagingRetinal Pigment EpitheliumStargardt DiseaseTomography, Optical CoherenceVisual AcuityABCA4 protein, humanATP-Binding Cassette TransportersABCA4fundus autofluorescencegrowth ratenatural history studyStargardt disease

Identifiers

PMID34946930
PMCPMC8701386
OpenAlexW4200341287

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.