Evidence map›Paper›PMID 34946880›Full record

ArticleGenes2021

MiR-138-5p Suppresses Cell Growth and Migration in Melanoma by Targeting Telomerase Reverse Transcriptase.

Estefanía Tarazón, Blanca de Unamuno Bustos, Rosa Murria Estal, Gema Pérez Simó, Antonio Sahuquillo Torralba, Javier Simarro, Sarai Palanca Suela, Rafael Botella Estrada

Open access · goldAbstract read
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Circular RNA circLAMC1 Promotes Liver Regeneration by Regulating the miR-138-5p/Gnai2 Axis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  3. Review
  4. Omics in Cutaneous Melanoma.Asian Pacific journal of cancer prevention : APJCP · 2025
    Review
  5. Article
  6. The Role of miR-138 in Cardiovascular Diseases.BioMed research international · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Effect of icariin on the HInternational journal of immunopathology and pharmacology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Estefanía TarazónDermatology and Tisular Regeneration Group, Health Research Institute La Fe, 46026 Valencia, Spain.ORCID 0000-0003-3466-2558
Blanca de Unamuno BustosDermatology and Tisular Regeneration Group, Health Research Institute La Fe, 46026 Valencia, Spain.
Rosa Murria EstalDermatology and Tisular Regeneration Group, Health Research Institute La Fe, 46026 Valencia, Spain.
Gema Pérez SimóClinical and Translational Cancer Research Group, Health Research Institute La Fe, 46026 Valencia, Spain.
Antonio Sahuquillo TorralbaDermatology and Tisular Regeneration Group, Health Research Institute La Fe, 46026 Valencia, Spain.ORCID 0000-0002-9354-7464
Javier SimarroClinical and Translational Cancer Research Group, Health Research Institute La Fe, 46026 Valencia, Spain.ORCID 0000-0003-3155-1713
Sarai Palanca SuelaClinical and Translational Cancer Research Group, Health Research Institute La Fe, 46026 Valencia, Spain.ORCID 0000-0003-0001-1060
Rafael Botella EstradaDermatology and Tisular Regeneration Group, Health Research Institute La Fe, 46026 Valencia, Spain.
Leitat Technological Center · ESHospital Universitari i Politècnic La Fe · ESUniversitat de València · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent evidence suggests the existence of a miRNA regulatory network involving human telomerase reverse transcriptase gene (

Indexed as

Gene Expression Regulation, EnzymologicGene Expression Regulation, NeoplasticCell Line, TumorCell MovementCell ProliferationGenes, Tumor SuppressorHumansMelanoma, ExperimentalMicroRNAsMutationPromoter Regions, GeneticRNA, NeoplasmTelomeraseMicroRNAsMIRN138 microRNA, humanRNA, NeoplasmTelomerasehTERTmelanomamiR-138-5p

Identifiers

PMID34946880
PMCPMC8701232
OpenAlexW3215112562

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.