Evidence map›Paper›PMID 34946862›Full record

ArticleGenes2021

Kalichamy Alagarasu, Himanshu Kaushal, Pooja Shinde, Mahadeo Kakade, Urmila Chaudhary, Vikram Padbidri, Shashikala A Sangle, Sonali Salvi, Ashish R Bavdekar, Pradeep D'costa and 1 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Normal butanol fraction ofFrontiers in veterinary science · 2025
    Article
  11. A Tale of Two Cytokines: IL-10 Blocks IFN-γ in Influenza A Virus-American journal of respiratory cell and molecular biology · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Kalichamy AlagarasuICMR-National Institute of Virology, Pune 411001, India.ORCID 0000-0003-1401-8589
Himanshu KaushalICMR-National Institute of Virology, Pune 411001, India.
Pooja ShindeICMR-National Institute of Virology, Pune 411001, India.
Mahadeo KakadeICMR-National Institute of Virology, Pune 411001, India.
Urmila ChaudharyICMR-National Institute of Virology, Pune 411001, India.ORCID 0000-0003-1509-5164
Vikram PadbidriJehangir Hospital Research Center, Pune 411001, India.
Shashikala A SangleDepartment of Medicine, BJ Medical College, Pune 411001, India.
Sonali SalviDepartment of Medicine, BJ Medical College, Pune 411001, India.
Ashish R BavdekarKEM Hospital Research Center, Pune 411001, India.
Pradeep D'costaKEM Hospital Research Center, Pune 411001, India.
Manohar Lal ChoudharyICMR-National Institute of Virology, Pune 411001, India.
ICMR-National Institute of Virology · INB. J. Medical College & Sassoon Hospital · INJehangir Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytokines are key modulators of immune response, and dysregulated production of proinflammatory and anti-inflammatory cytokines contributes to the pathogenesis of influenza A(H1N1)pdm09 virus infection. Cytokine production is impacted by single nucleotide polymorphisms (SNPs) in the genes coding for them. In the present study, SNPs in the

Indexed as

AllelesPolymorphism, Single NucleotideAdultBiomarkersFemaleHumansInfluenza A Virus, H1N1 SubtypeInfluenza, HumanInterleukin-10Interleukin-6MaleMiddle AgedSeverity of Illness IndexTumor Necrosis Factor-alphaBiomarkersIL10 protein, humanIL6 protein, humanInterleukin-10Interleukin-6TNF protein, humanTumor Necrosis Factor-alphacytokinesgene polymorphismsinfluenza A(H1N1)pdm09interleukinsTNF-α

Identifiers

PMID34946862
PMCPMC8700762
OpenAlexW3217074028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.