Evidence map›Paper›PMID 34946842›Full record

ArticleGenes2021

Investigation of Cerebellar Abiotrophy (CA), Lavender Foal Syndrome (LFS), and Severe Combined Immunodeficiency (SCID) Variants in a Cohort of Three MENA Region Horse Breeds.

Abdelhanine Ayad, Saria Almarzook, Omar Besseboua, Sofiane Aissanou, Katarzyna Piórkowska, Adrianna D Musiał, Monika Stefaniuk-Szmukier, Katarzyna Ropka-Molik

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Abdelhanine AyadDepartment of Environment and Biological Sciences, Faculty of Nature and Life Sciences, University of Bejaia, Bejaia 06000, Algeria.ORCID 0000-0002-9325-7889
Saria AlmarzookFaculty of Applied Sciences, University of Applied Sciences Europe, 10963 Berlin, Germany.
Omar BessebouaDepartment of Agronomic and Biotechnological Sciences, Faculty of Nature and Life Sciences, University H. Benbouali, Chlef 02000, Algeria.
Sofiane AissanouDepartment of Environment and Biological Sciences, Faculty of Nature and Life Sciences, University of Bejaia, Bejaia 06000, Algeria.
Katarzyna PiórkowskaDepartment of Animal Molecular Biology, National Research Institute of Animal Production, Krakowska 1, 32-083 Balice, Poland.ORCID 0000-0002-4368-9624
Adrianna D MusiałDepartment of Animal Molecular Biology, National Research Institute of Animal Production, Krakowska 1, 32-083 Balice, Poland.ORCID 0000-0002-4194-9402
Monika Stefaniuk-SzmukierDepartment of Animal Molecular Biology, National Research Institute of Animal Production, Krakowska 1, 32-083 Balice, Poland.ORCID 0000-0003-4158-771X
Katarzyna Ropka-MolikDepartment of Animal Molecular Biology, National Research Institute of Animal Production, Krakowska 1, 32-083 Balice, Poland.ORCID 0000-0002-8555-0495
National Research Institute of Animal Production · PLUniversity of Béjaïa · DZHassiba Benbouali University of Chlef · DZUniversity of Applied Sciences Europe · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic disorders in horses are mostly fatal or usually cause significant economic losses for breeders and owners. Here we studied a total of 177 Arabian, Barb and Arab-Barb horses from the Middle East and North Africa (MENA) using Sanger Sequencing and PCR-ACRS (polymerase chain reaction-artificially created restriction site) approaches to examine the genetic disorders in the studied horse breeds. We identified the genetic variations related to Cerebellar Abiotrophy (CA), Severe Combined Immunodeficiency (SCID) occurrence, and the studied population was free of the mutant allele determined Lavender Foal Syndrome (LFS). Overall, presented data showed that 15 of the studied horses are carriers of two genetic disorders; the investigated horse population showed that five Arabian horses were heterozygous for the CA-associated SNP (rs397160943). The SCID-deletion TCTCA within

Indexed as

Africa, NorthernAllelesAnimalsCerebellar DiseasesCohort StudiesHeterozygoteHorse DiseasesHorsesMiddle EastPolymorphism, Single NucleotideSevere Combined ImmunodeficiencyArab-Barb horsesArabian horsesBarb horsesCAgenetic disordersLFSmolecular biologySCID

Identifiers

PMID34946842
PMCPMC8701198
OpenAlexW3215642035

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.