Molecular Cytogenetic and Y Copy Number Analysis of a Reciprocal ECAY-ECA13 Translocation in a Stallion with Complete Meiotic Arrest.

Caitlin Castaneda, Agustin J Ruiz, Ahmed Tibary, Terje Raudsepp

Open access · goldAbstract read

In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.2field-weighted citation impact, top 37% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

Copy number variation of horse Y chromosome genes in normal equine populations and in horses with abnormal sex development and subfertility: relationship of copy number variations with Y haplogroups.G3 (Bethesda, Md.) · 2022
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Caitlin CastanedaDepartment of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0001-5910-9666

Agustin J RuizDepartment of Veterinary Clinical Sciences, Washington State University, Pullman, WA 99164, USA.

Ahmed TibaryDepartment of Veterinary Clinical Sciences, Washington State University, Pullman, WA 99164, USA.

Terje RaudseppDepartment of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0003-2276-475X

Texas A&M University · USWashington State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a detailed molecular cytogenetic analysis of a reciprocal translocation between horse (ECA) chromosomes Y and 13 in a Friesian stallion with complete meiotic arrest and azoospermia. We use dual-color fluorescence in situ hybridization with select ECAY and ECA13 markers and show that the translocation breakpoint in ECAY is in the multicopy region and in ECA13, at the centromere. One resulting derivative chromosome, Y;13p, comprises of ECAY heterochromatin (

Indexed as

AnimalsCentromereCytogenetic AnalysisCytogeneticsDNA Copy Number VariationsHeterochromatinHorsesMaleMeiosisTranslocation, GeneticY ChromosomeHeterochromatinazoospermiaFISHFriesian breedhorseMCSImeiotic executioner genesY-autosome translocation

Identifiers

PMID34946841

DOI10.3390/genes12121892

PMCPMC8701272

OpenAlexW3215780966

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.