Evidence map›Paper›PMID 34946674›Full record

ArticleMolecules (Basel, Switzerland)2021

Synthesis and Antimicrobial Activity of δ-Viniferin Analogues and Isosteres.

Luce Micaela Mattio, Cecilia Pinna, Giorgia Catinella, Loana Musso, Kasandra Juliet Pedersen, Karen Angeliki Krogfelt, Sabrina Dallavalle, Andrea Pinto

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Luce Micaela MattioDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Via Celoria 2, 20133 Milan, Italy.ORCID 0000-0003-0955-3982
Cecilia PinnaDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Via Celoria 2, 20133 Milan, Italy.
Giorgia CatinellaDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Via Celoria 2, 20133 Milan, Italy.ORCID 0000-0002-1887-1272
Loana MussoDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Via Celoria 2, 20133 Milan, Italy.ORCID 0000-0002-6838-7753
Kasandra Juliet PedersenInstitute of Molecular and Medical Biology, Roskilde University, 4000 Roskilde, Denmark.
Karen Angeliki KrogfeltInstitute of Molecular and Medical Biology, Roskilde University, 4000 Roskilde, Denmark.
Sabrina DallavalleDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Via Celoria 2, 20133 Milan, Italy.ORCID 0000-0002-8813-8922
Andrea PintoDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Via Celoria 2, 20133 Milan, Italy.ORCID 0000-0002-2501-3348

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The natural stilbenoid dehydro-δ-viniferin, containing a benzofuran core, has been recently identified as a promising antimicrobial agent. To define the structural elements relevant to its activity, we modified the styryl moiety, appended at C5 of the benzofuran ring. In this paper, we report the construction of stilbenoid-derived 2,3-diaryl-5-substituted benzofurans, which allowed us to prepare a focused collection of dehydro-δ-viniferin analogues. The antimicrobial activity of the synthesized compounds was evaluated against

Indexed as

Anti-Bacterial AgentsBenzofuransResorcinolsStilbenesMicrobial Sensitivity TestsStaphylococcus aureusAnti-Bacterial AgentsBenzofuransdelta-viniferinResorcinolsStilbenesantimicrobialsbenzofuran nucleusstilbenoidsviniferin derivatives

Identifiers

PMID34946674
PMCPMC8703454

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.