Evidence map›Paper›PMID 34946588›Full record

ArticleMolecules (Basel, Switzerland)2021

Crossing of the Cystic Barriers of

Céline Dard, Baptiste Leforestier, Flaviane Francisco Hilário, Mohamed Dit Mady Traoré, Marie-Ange Lespinasse, Basile Pérès, Marie-Carmen Molina, Rossimiriam Pereira de Freitas, Anne Milet, Danièle Maubon and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Antiviral Activity of a Cyclic Pro-Pro-Molecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Céline DardTeam Host-Pathogen Interactions and Immunity to Infection, Institute for Advanced Biosciences, INSERM, CNRSINSERM U1209, CNRS UMR 5309, Univ. Grenoble Alpes, 38000 Grenoble, France.
Baptiste LeforestierTeam SITH, CNRS UMR 5250, Univ. Grenoble Alpes, CNRS, DCM, 38000 Grenoble, France.ORCID 0000-0001-8547-6021
Flaviane Francisco HilárioTeam COMET, CNRS UMR 5063, Univ. Grenoble Alpes, CNRS, DPM, 38000 Grenoble, France.
Mohamed Dit Mady TraoréTeam COMET, CNRS UMR 5063, Univ. Grenoble Alpes, CNRS, DPM, 38000 Grenoble, France.
Marie-Ange LespinasseTeam COMET, CNRS UMR 5063, Univ. Grenoble Alpes, CNRS, DPM, 38000 Grenoble, France.
Basile PérèsTeam COMET, CNRS UMR 5063, Univ. Grenoble Alpes, CNRS, DPM, 38000 Grenoble, France.
Marie-Carmen MolinaTeam COMET, CNRS UMR 5063, Univ. Grenoble Alpes, CNRS, DPM, 38000 Grenoble, France.
Rossimiriam Pereira de FreitasDepartamento de Química, Universidade Federal de Minas Gerais, Av Pres Antônio Carlos, 6627, Pampulha, Belo Horizonte 31270-901, MG, Brazil.ORCID 0000-0001-6974-3724
Anne MiletTeam SITH, CNRS UMR 5250, Univ. Grenoble Alpes, CNRS, DCM, 38000 Grenoble, France.
Danièle MaubonTeam Host-Pathogen Interactions and Immunity to Infection, Institute for Advanced Biosciences, INSERM, CNRSINSERM U1209, CNRS UMR 5309, Univ. Grenoble Alpes, 38000 Grenoble, France.ORCID 0000-0002-9080-7638
Yung-Sing WongDepartamento de Química, Universidade Federal de Minas Gerais, Av Pres Antônio Carlos, 6627, Pampulha, Belo Horizonte 31270-901, MG, Brazil.ORCID 0000-0003-1038-9681
Centre National de la Recherche Scientifique · FRUniversidade Federal de Minas Gerais · BR

Funding

Agence Nationale de la Recherche ANR-10-EQPX-29-01Agence Nationale de la Recherche ANR-17-EURE-003Délégation Régionale Auvergne-Rhône-Alpes CPER07_13CIRA
6 · The paper itself

Abstract

FR235222 is a natural tetra-cyclopeptide with a strong inhibition effect on histone deacetylases, effective on mammalian cells as well as on intracellular apicomplexan parasites, such as

Indexed as

CoumarinsFluorescent DyesHistone Deacetylase InhibitorsHistone DeacetylasesModels, MolecularPeptides, CyclicToxoplasmacoumarinCoumarinsFluorescent DyesHistone Deacetylase InhibitorsHistone DeacetylasesPeptides, Cyclicbradyzoitecell-permeable agentcyclopeptideshistone deacetylasemolecular dynamicsToxoplasma gondii

Identifiers

PMID34946588
PMCPMC8708940
OpenAlexW4200333044

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.