Evidence map›Paper›PMID 34946555›Full record

ArticleMolecules (Basel, Switzerland)2021

In Vitro Antileishmanial and Antischistosomal Activities of Anemonin Isolated from the Fresh Leaves of

Betelhem Sirak, Kaleab Asres, Asrat Hailu, Mthandazo Dube, Norbert Arnold, Cecile Häberli, Jennifer Keiser, Peter Imming

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Antileishmanial Activities of Methanol Extract and Solvent Fraction ofAdvances in pharmacological and pharmaceutical sciences · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Molecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Betelhem SirakDepartment of Pharmaceutical Chemistry and Pharmacognosy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa P.O. Box 1176, Ethiopia.ORCID 0000-0001-9469-7192
Kaleab AsresDepartment of Pharmaceutical Chemistry and Pharmacognosy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa P.O. Box 1176, Ethiopia.
Asrat HailuDepartment of Microbiology, Immunology and Parasitology, Faculty of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa P.O. Box 1176, Ethiopia.
Mthandazo DubeDepartment of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, D-06120 Halle (Saale), Germany.ORCID 0000-0002-1043-0480
Norbert ArnoldDepartment of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, D-06120 Halle (Saale), Germany.
Cecile HäberliSwiss Tropical and Public Health Institute, Socinstr. 57, CH-4051 Basel, Switzerland.
Jennifer KeiserSwiss Tropical and Public Health Institute, Socinstr. 57, CH-4051 Basel, Switzerland.ORCID 0000-0003-0290-3521
Peter ImmingInstitut fuer Pharmazie, Martin-Luther-Universitaet Halle-Wittenberg, Kurt-Mothes-Str. 3, 06120 Halle (Saale), Germany.

Funding

Deutsche Forschungsgemeinschaft 432291016School of Graduate Studies of Addis Ababa University None
6 · The paper itself

Abstract

Leishmaniasis and schistosomiasis are neglected tropical diseases (NTDs) infecting the world's poorest populations. Effectiveness of the current antileishmanial and antischistosomal therapies are significantly declining, which calls for an urgent need of new effective and safe drugs. In Ethiopia fresh leaves of

Indexed as

AnimalsAntiprotozoal AgentsFuransLeishmaniaParasitic Sensitivity TestsPlant ExtractsPlant LeavesRanunculusSchistosoma mansonianemoninAntiprotozoal AgentsFuransPlant Extractsamastigotesanemoninantileishmanial activityfresh leavesLeishmania aethiopicaLeishmania donovanimacrophagepromastigotesRanunculus multifidusselectivity index

Identifiers

PMID34946555
PMCPMC8703683

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.