Evidence map›Paper›PMID 34946526›Full record

ArticleMolecules (Basel, Switzerland)2021

Confocal Raman Spectroscopic Imaging for Evaluation of Distribution of Nano-Formulated Hydrophobic Active Cosmetic Ingredients in Hydrophilic Films.

Louise Van Gheluwe, Emilie Munnier, Hichem Kichou, Kamilia Kemel, Frédéric Mahut, Marylène Vayer, Christophe Sinturel, Hugh J Byrne, Florent Yvergnaux, Igor Chourpa and 1 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Louise Van GheluweEA 6295 Nanomédicaments et Nanosondes, Faculté de Pharmacie, Université de Tours, 31 Avenue Monge, 37200 Tours, France.
Emilie MunnierEA 6295 Nanomédicaments et Nanosondes, Faculté de Pharmacie, Université de Tours, 31 Avenue Monge, 37200 Tours, France.ORCID 0000-0002-6691-4484
Hichem KichouEA 6295 Nanomédicaments et Nanosondes, Faculté de Pharmacie, Université de Tours, 31 Avenue Monge, 37200 Tours, France.
Kamilia KemelEA 6295 Nanomédicaments et Nanosondes, Faculté de Pharmacie, Université de Tours, 31 Avenue Monge, 37200 Tours, France.
Frédéric MahutUMR CNRS 7374-Université d'Orléans ICMN, 45071 Orléans, France.
Marylène VayerUMR CNRS 7374-Université d'Orléans ICMN, 45071 Orléans, France.
Christophe SinturelUMR CNRS 7374-Université d'Orléans ICMN, 45071 Orléans, France.
Hugh J ByrneFOCAS Research Institute, TU Dublin, City Campus, Kevin Street, Dublin 8, Ireland.ORCID 0000-0002-1735-8610
Florent YvergnauxBioeurope, Route d'Oulins, 28260 Anet, France.
Igor ChourpaEA 6295 Nanomédicaments et Nanosondes, Faculté de Pharmacie, Université de Tours, 31 Avenue Monge, 37200 Tours, France.
Franck BonnierEA 6295 Nanomédicaments et Nanosondes, Faculté de Pharmacie, Université de Tours, 31 Avenue Monge, 37200 Tours, France.

Funding

Ambition Recherche et Devellopement Centre Val de Loire 2017-00118114FEDER 2017-EX003256
6 · The paper itself

Abstract

Film-forming systems are highly relevant to the topical administration of active ingredients (AI) to the body. Enhanced contact with the skin can increase the efficacy of delivery and penetration during prolonged exposure. However, after the evaporation of volatile solvents to form a thin film, the distribution of the ingredient should remain homogenous in order to ensure the effectiveness of the formula. This is especially critical for the use of hydrophobic molecules that have poor solubility in hydrophilic films. In order to address this concern, hydroxyphenethyl esters (PHE) of

Indexed as

Membranes, ArtificialNanostructuresAdministration, TopicalCosmeticsDrug EvaluationHydrophobic and Hydrophilic InteractionsPlant OilsPomegranateSeedsSpectrum Analysis, RamanSuspensionsCosmeticsMembranes, ArtificialPlant OilsSuspensionsactive cosmetic ingredientsconfocal Raman imagingfilmmultivariate analysisnanosuspensionpolyvinyl alcoholquantitative analysis

Identifiers

PMID34946526
PMCPMC8707231

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.