Evidence map›Paper›PMID 34946249›Full record

ReviewMedicina (Kaunas, Lithuania)2021

Direct Endoscopic Necrosectomy: Timing and Technique.

Sergio Pinto, Saverio Bellizzi, Roberta Badas, Maria Laura Canfora, Erica Loddo, Simone Spada, Kareem Khalaf, Alessandro Fugazza, Silvio Bergamini

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06553651 (Necrosectomy With Cryotechnology for Accelerated Removal), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06553651 narecruitingnot on this mapstarted 2026, after this paper: background citation

Necrosectomy With Cryotechnology for Accelerated Removal

TypeinterventionalSponsorChristopher C. Thompson, MD, MScRan2026 to 2029Enrolled20ConditionsPancreatic Necrosis, Acute Pancreatitis, Acute Pancreatic Necrosis, NecrosisArmsCryotechnology Necrosectomy Procedure
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Endoscopic step up: When and how.Surgery open science · 2022
    Article
  9. Recent Advances in Biliopancreatic Endoscopy.Medicina (Kaunas, Lithuania) · 2022
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Sergio PintoDigestive Endoscopy Unit, Department of Surgical Sciences, University Hospital of Cagliari, 09042 Cagliari, Italy.ORCID 0000-0002-0326-4322
Saverio BellizziMedical Epidemiologist, Independent Consultant, 1202 Geneva, Switzerland.ORCID 0000-0002-4119-0803
Roberta BadasDigestive Endoscopy Unit, Department of Surgical Sciences, University Hospital of Cagliari, 09042 Cagliari, Italy.
Maria Laura CanforaDigestive Endoscopy Unit, Department of Surgical Sciences, University Hospital of Cagliari, 09042 Cagliari, Italy.
Erica LoddoDigestive Endoscopy Unit, Department of Surgical Sciences, University Hospital of Cagliari, 09042 Cagliari, Italy.ORCID 0000-0002-0504-8041
Simone SpadaDigestive Endoscopy Unit, Department of Surgical Sciences, University Hospital of Cagliari, 09042 Cagliari, Italy.
Kareem KhalafDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele, 20090 Milano, Italy.ORCID 0000-0002-5534-7533
Alessandro FugazzaDigestive Endoscopy Unit, Department of Gastroenterology, Humanitas Research Hospital-IRCCS, 20089 Rozzano, Italy.
Silvio BergaminiDigestive Endoscopy Unit, Department of Surgical Sciences, University Hospital of Cagliari, 09042 Cagliari, Italy.
University of Cagliari · ITHumanitas University · ITIRCCS Humanitas Research Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Walled-off pancreatic necrosis (WOPN) is one of the local complications of acute pancreatitis (AP). Several interventional techniques have been developed over the last few years. The purpose of this narrative review is to explore such methodologies, with specific focus on endoscopic drainage and direct endoscopic necrosectomy (DEN), through evaluation of their indications and timing for intervention. Findings indicated how, after the introduction of lumen-apposing metal stents (LAMS), DEN is becoming the favorite technique to treat WOPN, especially when large solid debris or infection are present. Additionally, DEN is associated with a lower adverse events rate and hospital stay, and with improved clinical outcome.

Indexed as

DrainagePancreatitis, Acute NecrotizingAcute DiseaseHumansRetrospective StudiesStentsTreatment Outcomeacute pancreatitisdirect endoscopic necrosectomyEUSLAMSpancreatic necrotic collectionwalled-off pancreatic necrosis

Identifiers

PMID34946249
PMCPMC8707414
OpenAlexW3217285287

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.