Evidence map›Paper›PMID 34946218›Full record

ArticleMicroorganisms2021

Virological and Parasitological Characterization of Mini-LEWE Minipigs Using Improved Screening Methods and an Overview of Data on Various Minipig Breeds.

Sabrina Halecker, Julia Metzger, Christina Strube, Ludwig Krabben, Benedikt Kaufer, Joachim Denner

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sabrina HaleckerInstitute of Virology, Freie Universität Berlin, 14163 Berlin, Germany.
Julia MetzgerResearch Group Veterinary Functional Genomics, Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany.ORCID 0000-0002-2089-8933
Christina StrubeInstitute for Parasitology, Centre for Infection Medicine, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.ORCID 0000-0002-9093-1006
Ludwig KrabbenInstitute of Virology, Freie Universität Berlin, 14163 Berlin, Germany.
Benedikt KauferInstitute of Virology, Freie Universität Berlin, 14163 Berlin, Germany.ORCID 0000-0003-1328-2695
Joachim DennerInstitute of Virology, Freie Universität Berlin, 14163 Berlin, Germany.ORCID 0000-0003-3244-6085
Freie Universität Berlin · DEUniversity of Veterinary Medicine Hannover, Foundation · DE

Funding

Deutsche Forschungsgemeinschaft TRR 127
6 · The paper itself

Abstract

Minipigs play an important role in biomedical research and have also been used as donor animals in xenotransplantation. To serve as a donor in xenotransplantation, the animals must be free of potential zoonotic viruses, bacteria and parasites. Porcine endogenous retroviruses (PERVs) are integrated in the genome of all pigs and cannot be eliminated as most of the other pig viruses can. PERV-A and PERV-B infect human cells in cell culture and are integrated in all pigs, whereas PERV-C infects only pig cells and it is found in many, but not all pigs. Minipigs are known for a high prevalence of recombinant PERV-A/C viruses able to infect human cells (Denner and Schuurman,

Indexed as

minipigspig virusesporcine endogenous retrovirusesxenotransplantation

Identifiers

PMID34946218
PMCPMC8706741
OpenAlexW4200548463

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.