Evidence map›Paper›PMID 34946035›Full record

ArticleMicroorganisms2021

Structural Diversity, Fitness Cost, and Stability of a

Ziyi Liu, Zhiqiang Wang, Xiaoyu Lu, Kai Peng, Sheng Chen, Susu He, Ruichao Li

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Molecular Insights into Carbapenem Resistance inInternational journal of molecular sciences · 2026
    Review
  5. Article
  6. Article
  7. Emergence of carbapenem-resistantMicrobiology spectrum · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Enhancement ofFrontiers in microbiology · 2025
    Article
  12. First report of a carbapenem-resistantCurrent research in microbial sciences · 2025
    Article
  13. Article
  14. Article
  15. Acquisition of plasmids from Shiga toxin-producing Escherichia coli strains had low or neutral fitness cost on commensal E. coli.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Ziyi LiuJiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Zhiqiang WangJiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.ORCID 0000-0001-6486-9600
Xiaoyu LuJiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.ORCID 0000-0002-1330-5925
Kai PengJiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Sheng ChenDepartment of Infectious Diseases and Public Health, Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Hong Kong 999077, China.ORCID 0000-0003-3526-7808
Susu HeState Key Laboratory of Pharmaceutical Biotechnology, Medical School of Nanjing University, Nanjing 210093, China.ORCID 0000-0002-2138-3421
Ruichao LiJiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.ORCID 0000-0001-8333-9891
Yangzhou University · CNChina Pharmaceutical University · CNCity University of Hong Kong · HK

Funding

Fundamental Research Funds for the Central Universities 14380470Natural Science Foundation of Jiangsu Province BK20180900Natural Science Foundation of Jiangsu Province BK20200316Priority Academic Program Development of Jiangsu Higher Education Institutions PAPD
6 · The paper itself

Abstract

Cointegrate/hybrid plasmids combine the genetic elements of two or more plasmids and generally carry abundant antimicrobial resistance determinants. Hence, the spread of cointegrate plasmids will accelerate the transmission of AMR genes. To evaluate the transmission risk caused by cointegrate plasmids, we investigated the structural diversity, fitness cost, and stability of a cointegrate plasmid in

Indexed as

blaNDM-1cointegrate plasmidfitness costplasmid stabilitystructural diversity

Identifiers

PMID34946035
PMCPMC8708245
OpenAlexW3215764374

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.