Evidence map›Paper›PMID 34945816›Full record

ArticleJournal of personalized medicine2021

Applicability of Pharmacogenomically Guided Medication Treatment during Hospitalization of At-Risk Minority Patients.

Loren Saulsberry, Keith Danahey, Merisa Middlestadt, Kevin J O'Leary, Edith A Nutescu, Thomas Chen, James C Lee, Gregory W Ruhnke, David George, Larry House and 11 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 4 institutions in 1 country.

Loren SaulsberryDepartment of Public Health Sciences, The University of Chicago, Chicago, IL 60637, USA.
Keith DanaheyCenter for Personalized Therapeutics, The University of Chicago, Chicago, IL 60637, USA.
Merisa MiddlestadtCenter for Personalized Therapeutics, The University of Chicago, Chicago, IL 60637, USA.
Kevin J O'LearyDivision of Hospital Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Edith A NutescuDepartment of Pharmacy Systems, Outcomes and Policy, College of Pharmacy, University of Illinois Chicago, Chicago, IL 60612, USA.
Thomas ChenSection of Hospital Medicine, Department of Medicine, The University of Chicago, Chicago, IL 60637, USA.
James C LeeDepartment of Pharmacy Practice, University of Illinois Chicago, Chicago, IL 60612, USA.ORCID 0000-0002-3101-7281
Gregory W RuhnkeSection of Hospital Medicine, Department of Medicine, The University of Chicago, Chicago, IL 60637, USA.
David GeorgeCenter for Personalized Therapeutics, The University of Chicago, Chicago, IL 60637, USA.
Larry HouseCenter for Personalized Therapeutics, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0003-2066-9855
Xander M R van WijkCenter for Personalized Therapeutics, The University of Chicago, Chicago, IL 60637, USA.
Kiang-Teck J YeoCenter for Personalized Therapeutics, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-4708-8420
Anish ChoksiDepartment of Pharmacy, The University of Chicago, Chicago, IL 60637, USA.
Seth W HartmanDepartment of Medicine, The University of Chicago, Chicago, IL 60637, USA.
Randall W KnoebelDepartment of Medicine, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-0166-4955
Paula N FriedmanCenter for Pharmacogenomics, Department of Pharmacology, Northwestern University, Chicago, IL 60611, USA.
Luke V RasmussenDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Mark J RatainCenter for Personalized Therapeutics, The University of Chicago, Chicago, IL 60637, USA.
Minoli A PereraCenter for Pharmacogenomics, Department of Pharmacology, Northwestern University, Chicago, IL 60611, USA.ORCID 0000-0002-1146-2791
David O MeltzerSection of Hospital Medicine, Department of Medicine, The University of Chicago, Chicago, IL 60637, USA.
Peter H O'DonnellCenter for Personalized Therapeutics, The University of Chicago, Chicago, IL 60637, USA.
University of Chicago · USNorthwestern University · USUniversity of Illinois Chicago · USChicago Department of Public Health · US

Funding

Health Equity and Risk Communication in PharmacogenomicsK08HG011505 · NHGRI · UNIVERSITY OF CHICAGO · PI SAULSBERRY, LOREN · 2020 to 2024
$836k
NHGRI NIH HHS K08 HG011505NIH HHS 1U54MD010723NIH HHS K08 HG011505The University of Chicago Comprehensive Cancer Center support grantThe William F. O'Connor Foundation grant
6 · The paper itself

Abstract

Known disparities exist in the availability of pharmacogenomic information for minority populations, amplifying uncertainty around clinical utility for these groups. We conducted a multi-site inpatient pharmacogenomic implementation program among self-identified African-Americans (AA;

Indexed as

implementationminority populationspharmacogenomics

Identifiers

PMID34945816
PMCPMC8709436
OpenAlexW4200600425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.