Evidence map›Paper›PMID 34945798›Full record

ArticleJournal of personalized medicine2021

Allogeneic Bone-Marrow Mesenchymal Stem Cell with Moldable Cryogel for Craniofacial Bone Regeneration.

Cheng-Feng Chu, Shih-Hsuan Mao, Victor Bong-Hang Shyu, Chih-Hao Chen, Chien-Tzung Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cheng-Feng ChuDepartment of Plastic and Reconstructive Surgery, Keelung Chang Gung Memorial Hospital, Keelung 204, Taiwan.ORCID 0000-0001-8233-7720
Shih-Hsuan MaoDepartment of Plastic and Reconstructive Surgery, College of Medicine, Chang Gung University, Linkou Chang Gung Memorial Hospital, Craniofacial Research Center, Taoyuan 333, Taiwan.
Victor Bong-Hang ShyuDepartment of Plastic and Reconstructive Surgery, Keelung Chang Gung Memorial Hospital, Keelung 204, Taiwan.
Chih-Hao ChenDepartment of Plastic and Reconstructive Surgery, Keelung Chang Gung Memorial Hospital, Keelung 204, Taiwan.ORCID 0000-0001-7213-2596
Chien-Tzung ChenDepartment of Plastic and Reconstructive Surgery, College of Medicine, Chang Gung University, Linkou Chang Gung Memorial Hospital, Craniofacial Research Center, Taoyuan 333, Taiwan.

Funding

Chang Gung Memorial Hospital CRRPG2G0011-12Ministry of Science and Technology NMRPG2G6061-2
6 · The paper itself

Abstract

Allogeneic bone-marrow mesenchymal stem cells (BMSCs) can promote bone regeneration and substitute for autologous BMSCs if autologous sources are unavailable, but the efficacy of bone regeneration by allogeneic BMSCs is still inconsistent. A Lewis rat cranium defect model was used to investigate the efficacy of bone regeneration between autologous and allogeneic BMSCs in gelatin-nanohydroxyapatite cryogel scaffolds. BMSCs from Wistar rats served as the allogeneic cell lineage. The full-thickness cranium defects were treated by either blank control, cryogel only, allogeneic BMSC-seeded cryogel, or autologous BMSC-seeded cryogel (

Indexed as

allogeneic cellular transplantationbone-marrow mesenchymal stem cellsbone regenerationcryogel

Identifiers

PMID34945798
PMCPMC8704672

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.