ArticleJournal of personalized medicine2021
A Novel Noninvasive Technique for Intracranial Pressure Waveform Monitoring in Critical Care.
Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06423469 (A Multicenter Observational Cohort for the Determination of Noninvasive Intracranial Pressure Waveforms Role in Traumatic Brain Injury), which is not on this map. Cited by 53 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Multicenter Observational Cohort for the Determination of Noninvasive Intracranial Pressure Waveforms Role in Traumatic Brain Injury
Who cites it
53 citing papers in PubMed, 90 citations in OpenAlex.
- Noninvasive intracranial pressure waveforms for estimation of intracranial hypertension and outcome prediction in acute brain-injured patients.Journal of clinical monitoring and computing · 2023Trial
- Intracranial Pressure Estimation Using B4C Device: A Systematic Review on the Validation Studies.Neurocritical care · 2026Review
- Neuromonitoring in the Decompressed Brain: Rethinking Physiology, Monitoring, and Thresholds After Decompressive Craniectomy.Neurocritical care · 2026Article
- Impaired Intracranial Compliance: A New Hypertension-Mediated Brain Organ Damage?High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026Article
- Neuroworsening in traumatic brain injury: A consensus of the Latin American Brain Injury Consortium (LABIC) and the Latin American Federation of Neurosurgical Societies (FLANC) expert group.Neurosurgical review · 2026Article
- Non-invasive intracranial pressure estimation in the intensive care unit: narrative review of methods and clinical applications.Intensive care medicine · 2026Review
- A noninvasive method for assessing optimal cerebral perfusion pressure.Critical care (London, England) · 2026Observational
- First-in-Human Prospective, Observational, and Comparative Clinical Study of Simultaneous Invasive and Non-Invasive Intracranial Pressure Pulse Wave Monitoring.Sensors (Basel, Switzerland) · 2026Observational
- Non-invasive ICP monitoring when invasive systems are available in the care of acute brain injured patients: a clinical approach.Journal of anesthesia, analgesia and critical care · 2026Article
- Invasive and Noninvasive Intracranial Pressure Pulse Waveform in Neurocritical Care Patients with Different Cranium Integrity.Neurocritical care · 2026Article
- Impact of hemodynamic management guided by intracranial compliance on the outcome of critically ill patients - preliminary results and exploratory economic evaluation.Cost effectiveness and resource allocation : C/E · 2026Article
- Non-Invasive Multidimensional Capacitive Sensing for In Vivo Traumatic Brain Injury Monitoring.Advanced materials technologies · 2026Article
- Exploring Cerebrospinal Compensatory Zones Using a Noninvasive Approach.Neurocritical care · 2025Observational
- Clinical Performance of the Brain4care System for Noninvasive Detection of Intracranial Hypertension.Neurocritical care · 2025Article
- Management of intracranial hypertension with and without invasive intracranial pressure monitoring.World journal of critical care medicine · 2025Review
- The value of dynamic cerebral compliance monitoring after pediatric traumatic brain injury: a STARSHIP study sub-analysis.Critical care (London, England) · 2025Observational
- Low-Cost Strategies for the Development of Neurocritical Care in Resource-Limited Settings.Neurocritical care · 2025Review
- The dawn of noninvasive intracranial compliance waveforms: a call for the B-ICONIC improvement and expansion.Intensive care medicine · 2025Article
- Noninvasive Method Using Mechanical Extensometer for the Estimation of Intracranial Compliance by Repeated Measures Agreement Analysis.Neurocritical care · 2025Article
- Hypertension, blood-brain barrier disruption and changes in intracranial pressure.The Journal of physiology · 2025Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe validated a new noninvasive tool (B4C) to assess intracranial pressure waveform (ICPW) morphology in a set of neurocritical patients, correlating the data with ICPW obtained from invasive catheter monitoring. MATERIALS AND
methodsPatients undergoing invasive intracranial pressure (ICP) monitoring were consecutively evaluated using the B4C sensor. Ultrasound-guided manual internal jugular vein (IJV) compression was performed to elevate ICP from the baseline. ICP values, amplitudes, and time intervals (P2/P1 ratio and time-to-peak [TTP]) between the ICP and B4C waveform peaks were analyzed.
resultsAmong 41 patients, the main causes for ICP monitoring included traumatic brain injury, subarachnoid hemorrhage, and stroke. Bland-Altman's plot indicated agreement between the ICPW parameters obtained using both techniques. The strongest Pearson's correlation for P2/P1 and TTP was observed among patients with no cranial damage (r = 0.72 and 0.85, respectively) to the detriment of those who have undergone craniotomies or craniectomies. P2/P1 values of 1 were equivalent between the two techniques (area under the receiver operator curve [AUROC], 0.9) whereas B4C cut-off 1.2 was predictive of intracranial hypertension (AUROC 0.9,
conclusionB4C provided biometric amplitude ratios correlated with ICPW variation morphology and is useful for noninvasive critical care monitoring.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.