Evidence map›Paper›PMID 34945746›Full record

ArticleJournal of personalized medicine2021

Prognostic Value of C-Reactive Protein to Lymphocyte Ratio (CLR) in Emergency Department Patients with SARS-CoV-2 Infection.

Ndenga Tonduangu, Pierrick Le Borgne, François Lefebvre, Karine Alame, Lise Bérard, Yannick Gottwalles, Lauriane Cipolat, Stéphane Gennai, Pascal Bilbault, Charles-Eric Lavoignet and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  8. The Role of Hemogram-derived Ratios in COVID-19 Severity Stratification in a Primary Healthcare Facility.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2023
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  12. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Ndenga TonduanguEmergency Department, Regional Hospital of Metz-Thionville and France, 57000 Metz, France.
Pierrick Le BorgneEmergency Department, University Hospital of Strasbourg, 67000 Strasbourg, France.ORCID 0000-0001-9141-6439
François LefebvreDepartment of Public Health, University Hospital of Strasbourg, 67000 Strasbourg, France.
Karine AlameEmergency Department, University Hospital of Strasbourg, 67000 Strasbourg, France.
Lise BérardEmergency Department, Haguenau Hospital, 67500 Haguenau, France.
Yannick GottwallesEmergency Department, Colmar Hospital, 68026 Colmar, France.
Lauriane CipolatEmergency Department, Regional Hospital of Metz-Thionville and France, 57000 Metz, France.
Stéphane GennaiEmergency Department, Reims University Hospital, 51100 Reims, France.
Pascal BilbaultEmergency Department, University Hospital of Strasbourg, 67000 Strasbourg, France.ORCID 0000-0003-0904-4600
Charles-Eric LavoignetEmergency Department, Hôpital Nord Franche Comté, 90000 Belfort, France.
Laure Abensur VuillaumeEmergency Department, Regional Hospital of Metz-Thionville and France, 57000 Metz, France.ORCID 0000-0003-2527-8458
Crems Network Clinical Research In Emergency Medicine And Sepsis Clr
Centre Hospitalier Régional de Metz-Thionville · FRInserm · FRCentre Hospitalier Universitaire de Reims · FRHopitaux Civils de Colmar · FRL'Hôpital Nord Franche-Comté · FRUniversité de Strasbourg · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Introduction: According to recent studies, the ratio of C-reactive-protein to lymphocyte is more sensitive and specific than other biomarkers associated to systemic inflammatory processes. This study aimed to determine the prognostic value of CLR on COVID-19 severity and mortality at emergency department (ED) admission. (2) Methods: Between 1 March and 30 April 2020, we carried out a multicenter and retrospective study in six major hospitals of northeast France. The cohort was composed of patients hospitalized for a confirmed diagnosis of moderate to severe COVID-19. (3) Results: A total of 1,035 patients were included in this study. Factors associated with infection severity were the CLR (OR: 1.001, CI 95%: (1.000-1.002),

Indexed as

CLRCOVID-19mortalityseverity

Identifiers

PMID34945746
PMCPMC8706788
OpenAlexW3216382425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.