Evidence map›Paper›PMID 34945738›Full record

ArticleJournal of personalized medicine2021

Monocyte/Lymphocyte Ratio and MCHC as Predictors of Collateral Carotid Artery Disease-Preliminary Report.

Tomasz Urbanowicz, Michał Michalak, Anna Olasińska-Wiśniewska, Michał Rodzki, Aleksandra Krasińska, Bartłomiej Perek, Zbigniew Krasiński, Marek Jemielity

Abstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Observational
  2. Article
  3. The effectiveness of three months EGFR-CTH therapy in palliative colorectal cancer.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Observational
  10. The Association Between Mean Corpuscular Hemoglobin Concentration and Prognosis in Patients with Acute Pulmonary Embolism: A Retrospective Cohort Study.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tomasz UrbanowiczCardiac Surgery and Transplantology Department, Poznan University of Medical Sciences, 61-848 Poznan, Poland.ORCID 0000-0001-8080-2764
Michał MichalakDepartment of Computer Science and Statistics, Poznan University of Medical Sciences, 61-848 Poznan, Poland.ORCID 0000-0002-2852-3984
Anna Olasińska-WiśniewskaCardiac Surgery and Transplantology Department, Poznan University of Medical Sciences, 61-848 Poznan, Poland.ORCID 0000-0002-4213-8708
Michał RodzkiCardiac Surgery and Transplantology Department, Poznan University of Medical Sciences, 61-848 Poznan, Poland.
Aleksandra KrasińskaDepartment of Ophtalmology, Poznan University of Medical Sciences, 61-848 Poznan, Poland.ORCID 0000-0001-8934-2506
Bartłomiej PerekCardiac Surgery and Transplantology Department, Poznan University of Medical Sciences, 61-848 Poznan, Poland.ORCID 0000-0003-2398-9571
Zbigniew KrasińskiDepartment of Vascular, Endovascular Surgery, Poznan University of Medical Science, 61-848 Poznan, Poland.
Marek JemielityCardiac Surgery and Transplantology Department, Poznan University of Medical Sciences, 61-848 Poznan, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCarotid artery disease accounts for 30% of ischemic strokes in the general population. Numerous biomarkers have been investigated for predicting either the progression or the severity of the disease. The aim of this retrospective study was to compare hematologic indices among patients referred for surgical interventions due to severe carotid disease.

methodsIn total, 135 patients (87 (64.4%) men and 48 (35.6%) women) with a mean age of 70 ± 8 years who underwent surgical carotid intervention were enrolled into the study.

resultsA Mann-Whitney test for independent samples revealed significant differences in monocyte to lymphocyte ratio (MLR) and mean corpuscular hemoglobin concentration (MCHC) between patients with one and two (collateral) carotid diseases. The cut-off value for MLR was 0.3 (AUC = 0.654,

conclusionsMLR above 0.3 and MCHC above 21.6 have predictive values for colleterial carotid stenosis and may be used as easily accessible indicators for atherosclerosis severity.

Indexed as

carotid stenosis 3MCHC 2MLR 1

Identifiers

PMID34945738
PMCPMC8707882

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.