Evidence map›Paper›PMID 34945682›Full record

ReviewFoods (Basel, Switzerland)2021

Lactic Acid Bacteria as Antimicrobial Agents: Food Safety and Microbial Food Spoilage Prevention.

Salam A Ibrahim, Raphael D Ayivi, Tahl Zimmerman, Shahida Anusha Siddiqui, Ammar B Altemimi, Hafize Fidan, Tuba Esatbeyoglu, Reza Vaseghi Bakhshayesh

Open access · goldAbstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 133 papers.

0numbers the graph read from it
0cells of the map it votes in
133citing papers in PubMed
26.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

133 citing papers in PubMed, 330 citations in OpenAlex.

  1. Article
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  7. Review
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  10. Article
  11. DualFoods (Basel, Switzerland) · 2026
    Article
  12. Biological Control ofFoods (Basel, Switzerland) · 2026
    Article
  13. Review
  14. Article
  15. Article
  16. In vitro characterization of probiotic properties of isolated and grown co-cultures on halophyte-based substrate.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  17. Review
  18. Review
  19. Article
  20. Article

73 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 5 countries.

Salam A IbrahimFood and Nutritional Sciences Program, North Carolina A&T State University, Greensboro, NC 27411, USA.ORCID 0000-0001-5395-9993
Raphael D AyiviFood and Nutritional Sciences Program, North Carolina A&T State University, Greensboro, NC 27411, USA.ORCID 0000-0001-6671-7715
Tahl ZimmermanFood and Nutritional Sciences Program, North Carolina A&T State University, Greensboro, NC 27411, USA.
Shahida Anusha SiddiquiDepartment of Biotechnology and Sustainability, Technical University of Munich (TUM), 94315 Straubing, Germany.ORCID 0000-0001-6942-4408
Ammar B AltemimiDepartment of Food Science, College of Agriculture, University of Basrah, Basrah 61004, Iraq.ORCID 0000-0001-7750-5988
Hafize FidanDepartment of Nutrition and Tourism, University of Food Technologies, 26 Maritza Blvd., 40002 Plovdiv, Bulgaria.
Tuba EsatbeyogluInstitute of Food Science and Human Nutrition, Gottfried Wilhelm Leibniz University Hannover, Am Kleinen Felde 30, 30167 Hannover, Germany.ORCID 0000-0003-2413-6925
Reza Vaseghi BakhshayeshDepartment of Food Biotechnology, Branch for Northwest & West Region, Agricultural Biotechnology Research Institute of Iran, Agricultural Research, Education and Extension Organization (AREEO), Tabriz 5355179854, Iran.ORCID 0000-0003-1499-2832
North Carolina Agricultural and Technical State University · USGerman Institute of Food Technologies · DELeibniz University Hannover · DEUniversity of Basrah · IQUniversity of Food Technologies · BGUniversity of Tabriz · IR

Funding

National Institute of Food and Agriculture NC.X337-5-21-170-1 and NC.X341-5-21-170-1
6 · The paper itself

Abstract

In the wake of continual foodborne disease outbreaks in recent years, it is critical to focus on strategies that protect public health and reduce the incidence of foodborne pathogens and spoilage microorganisms. Currently, there are limitations associated with conventional microbial control methods, such as the use of chemical preservatives and heat treatments. For example, such conventional treatments adversely impact the sensorial properties of food, resulting in undesirable organoleptic characteristics. Moreover, the growing consumer advocacy for safe and healthy food products, and the resultant paradigm shift toward clean labels, have caused an increased interest in natural and effective antimicrobial alternatives. For instance, natural antimicrobial elements synthesized by lactic acid bacteria (LAB) are generally inhibitory to pathogens and significantly impede the action of food spoilage organisms. Bacteriocins and other LAB metabolites have been commercially exploited for their antimicrobial properties and used in many applications in the dairy industry to prevent the growth of undesirable microorganisms. In this review, we summarized the natural antimicrobial compounds produced by LAB, with a specific focus on the mechanisms of action and applications for microbial food spoilage prevention and disease control. In addition, we provide support in the review for our recommendation for the application of LAB as a potential alternative antimicrobial strategy for addressing the challenges posed by antibiotic resistance among pathogens.

Indexed as

antimicrobialbacteriocinbiopreservationfoodborne pathogenslactic acid bacteria (LAB)

Identifiers

PMID34945682
PMCPMC8701396
OpenAlexW4200271266

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.