Evidence map›Paper›PMID 34945630›Full record

ReviewFoods (Basel, Switzerland)2021

Nutrition and Physical Activity-Induced Changes in Gut Microbiota: Possible Implications for Human Health and Athletic Performance.

Vittoria Cella, Viviana M Bimonte, Claudia Sabato, Antonio Paoli, Carlo Baldari, Matteo Campanella, Andrea Lenzi, Elisabetta Ferretti, Silvia Migliaccio

Registry-linked trialAbstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06408610 (Moderate Continuous Versus High Interval Intensity Training on Gut Dysbiosis and Glucagon Like Peptide Hormone in Irritable Bowel Syndrome), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06408610 nacompletednot on this mapstarted 2024, after this paper: background citation

Moderate Continuous Versus High Interval Intensity Training on Gut Dysbiosis and Glucagon Like Peptide Hormone in Irritable Bowel Syndrome

TypeinterventionalSponsorCairo UniversityRan2024 to 2025Enrolled66ConditionsIrritable Bowel Syndrome, Obesity, DysbiosisArmsmoderate intensity continuous training
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vittoria CellaDepartment of Movement, Human and Health Sciences, University Foro Italico, 00135 Rome, Italy.
Viviana M BimonteDepartment of Movement, Human and Health Sciences, University Foro Italico, 00135 Rome, Italy.
Claudia SabatoDepartment of Experimental Medicine, University Sapienza, 00161 Rome, Italy.ORCID 0000-0001-7533-4660
Antonio PaoliDepartment of Biomedical Sciences, University of Padua, 35143 Padua, Italy.ORCID 0000-0003-0474-4229
Carlo BaldariDepartment of Theoretical and Applied Sciences, eCampus University, 22060 Novedrate, Italy.ORCID 0000-0001-6227-3571
Matteo CampanellaDepartment of Theoretical and Applied Sciences, eCampus University, 22060 Novedrate, Italy.ORCID 0000-0002-7222-7701
Andrea LenziDepartment of Experimental Medicine, University Sapienza, 00161 Rome, Italy.
Elisabetta FerrettiDepartment of Experimental Medicine, University Sapienza, 00161 Rome, Italy.ORCID 0000-0001-7265-6429
Silvia MigliaccioDepartment of Movement, Human and Health Sciences, University Foro Italico, 00135 Rome, Italy.ORCID 0000-0002-4563-6630

Funding

Ministry of Education, Universities and Research PRIN201793XZ5AMinistry of Education, Universities and Research PRIN2017HBHA98_004
6 · The paper itself

Abstract

The gut microbiota is a complex heterogeneous microbial community modulated by endogenous and exogenous factors. Among the external causes, nutrition as well as physical activity appear to be potential drivers of microbial diversity, both at the taxonomic and functional level, likely also influencing endocrine system, and acting as endocrine organ itself. To date, clear-cut data regarding which microbial populations are modified, and by which mechanisms are lacking. Moreover, the relationship between the microbial shifts and the metabolic practical potential of the gut microbiota is still unclear. Further research by longitudinal and well-designed studies is needed to investigate whether microbiome manipulation may be an effective tool for improving human health and, also, performance in athletes, and whether these effects may be then extended to the overall health promotion of general populations. In this review, we evaluate and summarize the current knowledge regarding the interaction and cross-talks among hormonal modifications, physical performance, and microbiota content and function.

Indexed as

athletesexercisegut microbiotahealthhormonesmicrobial compositionphysical performance

Identifiers

PMID34945630
PMCPMC8700881

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.