Evidence map›Paper›PMID 34945314›Full record

ReviewMicromachines2021

Point-of-Care Testing-The Key in the Battle against SARS-CoV-2 Pandemic.

Florina Silvia Iliescu, Ana Maria Ionescu, Larisa Gogianu, Monica Simion, Violeta Dediu, Mariana Carmen Chifiriuc, Gratiela Gradisteanu Pircalabioru, Ciprian Iliescu

Abstract readReview
In one paragraph

Review in Micromachines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Streptavidin-DisplayingSensors (Basel, Switzerland) · 2026
    Article
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  3. Review
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  8. Article
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  12. Advances in the Rapid Diagnostic of Viral Respiratory Tract Infections.Frontiers in cellular and infection microbiology · 2022
    Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Florina Silvia IliescuNational Institute for Research and Development in Microtechnologies, IMT-Bucharest, 077190 Bucharest, Romania.
Ana Maria IonescuNational Institute for Research and Development in Microtechnologies, IMT-Bucharest, 077190 Bucharest, Romania.
Larisa GogianuNational Institute for Research and Development in Microtechnologies, IMT-Bucharest, 077190 Bucharest, Romania.
Monica SimionNational Institute for Research and Development in Microtechnologies, IMT-Bucharest, 077190 Bucharest, Romania.
Violeta DediuNational Institute for Research and Development in Microtechnologies, IMT-Bucharest, 077190 Bucharest, Romania.ORCID 0000-0002-5698-303X
Mariana Carmen ChifiriucResearch Institute of University of Bucharest, University of Bucharest, 050095 Bucharest, Romania.ORCID 0000-0001-6098-1857
Gratiela Gradisteanu PircalabioruResearch Institute of University of Bucharest, University of Bucharest, 050095 Bucharest, Romania.
Ciprian IliescuNational Institute for Research and Development in Microtechnologies, IMT-Bucharest, 077190 Bucharest, Romania.ORCID 0000-0001-7042-5248

Funding

Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii PN-III-P2-2.1-SOL-2020-0090-Contract 13Sol/15.06.2020Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii PN-III-P4-ID-PCE-2020-186 Contract PCE 180/17/02/2021
6 · The paper itself

Abstract

The deleterious effects of the coronavirus disease 2019 (COVID-19) pandemic urged the development of diagnostic tools to manage the spread of disease. Currently, the "gold standard" involves the use of quantitative real-time polymerase chain reaction (qRT-PCR) for SARS-CoV-2 detection. Even though it is sensitive, specific and applicable for large batches of samples, qRT-PCR is labour-intensive, time-consuming, requires trained personnel and is not available in remote settings. This review summarizes and compares the available strategies for COVID-19: serological testing, Point-of-Care Testing, nanotechnology-based approaches and biosensors. Last but not least, we address the advantages and limitations of these methods as well as perspectives in COVID-19 diagnostics. The effort is constantly focused on understanding the quickly changing landscape of available diagnostic testing of COVID-19 at the clinical levels and introducing reliable and rapid screening point of care testing. The last approach is key to aid the clinical decision-making process for infection control, enhancing an appropriate treatment strategy and prompt isolation of asymptomatic/mild cases. As a viable alternative, Point-of-Care Testing (POCT) is typically low-cost and user-friendly, hence harbouring tremendous potential for rapid COVID-19 diagnosis.

Indexed as

detectionepidemicpoint of care testingSARS-CoV-2 variants

Identifiers

PMID34945314
PMCPMC8708595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.