Evidence map›Paper›PMID 34945257›Full record

ArticleJournal of clinical medicine2021

Time Course of Acute Vertebral Fractures: A Prospective Multicenter Cohort Study.

Hiroyuki Inose, Tsuyoshi Kato, Shinichi Shirasawa, Shinji Takahashi, Masatoshi Hoshino, Yu Yamato, Yu Matsukura, Takashi Hirai, Toshitaka Yoshii, Atsushi Okawa

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Incidence and prognostic factors of residual back pain in patients treated for osteoporotic vertebral compression fractures: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Pooled it
  2. Article
  3. Bracing versus balloon kyphoplasty for acute osteoporotic vertebral fractures with poor prognostic radiological factors: a propensity score-matched comparison.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  4. Controlling Nutritional Status (CONUT) score as a key predictor of disability following conservative treatment of osteoporotic vertebral fractures.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hiroyuki InoseDepartment of Orthopedic and Trauma Research, Graduate School, Tokyo Medical and Dental University, Tokyo 108-0075, Japan.ORCID 0000-0003-4195-2545
Tsuyoshi KatoDepartment of Orthopaedics, Ome Municipal General Hospital, Tokyo 198-0042, Japan.
Shinichi ShirasawaDepartment of Orthopaedics, Suwa Central Hospital, Nagano 391-8503, Japan.
Shinji TakahashiDepartment of Orthopedic Surgery, Graduate School of Medicine, Osaka City University, Osaka 545-8585, Japan.ORCID 0000-0002-6906-5406
Masatoshi HoshinoDepartment of Orthopedic Surgery, Osaka City General Hospital, Osaka 534-0021, Japan.
Yu YamatoDivision of Geriatric Musculoskeletal Health, Hamamatsu University School of Medicine, Shizuoka 431-3192, Japan.
Yu MatsukuraDepartment of Orthopaedics, Graduate School, Tokyo Medical and Dental University, Tokyo 108-0075, Japan.
Takashi HiraiDepartment of Orthopaedics, Graduate School, Tokyo Medical and Dental University, Tokyo 108-0075, Japan.ORCID 0000-0001-6200-0100
Toshitaka YoshiiDepartment of Orthopaedics, Graduate School, Tokyo Medical and Dental University, Tokyo 108-0075, Japan.
Atsushi OkawaDepartment of Orthopaedics, Graduate School, Tokyo Medical and Dental University, Tokyo 108-0075, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To date, it is still unclear how fresh osteoporotic vertebral fractures (OVFs) affect the patient's quality of life and low back pain during a follow-up period of more than 1 year. In the previous trial, women with fresh OVF were randomized to rigid or soft brace for 12 weeks, then both groups were followed for the subsequent 48 weeks. In women completing this trial at our affiliated hospitals, we conducted a follow-up study to investigate the long-term course of an acute vertebral fracture in terms of pain and quality of life. When comparing visual analog scale scores for low back pain and European Quality of Life-5 Dimensions Questionnaire scores between consecutive time points, a significant difference was found between 0 and 12 weeks, but not between 12 and 48 weeks or between 48 weeks and final follow-up. A total 25% had residual low back pain at the final follow-up. A stepwise logistic regression analysis identified age and previous vertebral fracture as predictors of residual low back pain at the final follow-up. Therefore, the degree of low back pain and impairment of the quality of life improved by 12 weeks after injury and did not change thereafter until a mean follow-up of 5.3 years.

Indexed as

osteoporotic vertebral fracturequality of liferesidual painvisual analog scale

Identifiers

PMID34945257
PMCPMC8704362

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.