Evidence map›Paper›PMID 34945256›Full record

ArticleJournal of clinical medicine2021

Uveitis and Other Ocular Complications Following COVID-19 Vaccination.

Elena Bolletta, Danilo Iannetta, Valentina Mastrofilippo, Luca De Simone, Fabrizio Gozzi, Stefania Croci, Martina Bonacini, Lucia Belloni, Alessandro Zerbini, Chantal Adani and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 4 pooled it
22.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 4 syntheses or guidelines pooled it, 132 citations in OpenAlex.

  1. Pooled it
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  16. Uveal effusion syndrome following COVID-19 vaccination.American journal of ophthalmology case reports · 2023
    Article
  17. Review
  18. Article
  19. Vogt-Koyanagi-Harada Disease and COVID.Journal of clinical medicine · 2023
    Review
  20. Ocular manifestations following COVID-19 vaccination.Journal of ophthalmic inflammation and infection · 2023
    Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Elena BollettaOcular Immunology Unit, Azienda USL-IRCCS, 42123 Reggio Emilia, Italy.ORCID 0000-0003-0292-0153
Danilo IannettaOphthalmology Unit, Azienda USL-IRCCS, 42123 Reggio Emilia, Italy.
Valentina MastrofilippoOcular Immunology Unit, Azienda USL-IRCCS, 42123 Reggio Emilia, Italy.
Luca De SimoneOcular Immunology Unit, Azienda USL-IRCCS, 42123 Reggio Emilia, Italy.ORCID 0000-0003-1471-1914
Fabrizio GozziOcular Immunology Unit, Azienda USL-IRCCS, 42123 Reggio Emilia, Italy.ORCID 0000-0002-4147-5534
Stefania CrociClinical Immunology, Allergy and Advanced Biotechnologies Unit, Azienda USL-IRCCS, 42123 Reggio Emilia, Italy.ORCID 0000-0002-8622-0439
Martina BonaciniClinical Immunology, Allergy and Advanced Biotechnologies Unit, Azienda USL-IRCCS, 42123 Reggio Emilia, Italy.ORCID 0000-0002-6830-6781
Lucia BelloniClinical Immunology, Allergy and Advanced Biotechnologies Unit, Azienda USL-IRCCS, 42123 Reggio Emilia, Italy.
Alessandro ZerbiniClinical Immunology, Allergy and Advanced Biotechnologies Unit, Azienda USL-IRCCS, 42123 Reggio Emilia, Italy.
Chantal AdaniOcular Immunology Unit, Azienda USL-IRCCS, 42123 Reggio Emilia, Italy.ORCID 0000-0002-2477-5463
Luigi FontanaOphthalmology Unit, DIMES, Alma Mater Studiorum, University of Bologna, S. Orsola-Malpighi Teaching Hospital, 40138 Bologna, Italy.ORCID 0000-0003-3877-0417
Carlo SalvaraniRheumatology Unit, Azienda USL-IRCCS, 42123 Reggio Emilia, Italy.
Luca CiminoOcular Immunology Unit, Azienda USL-IRCCS, 42123 Reggio Emilia, Italy.ORCID 0000-0001-7956-9950
Istituti di Ricovero e Cura a Carattere Scientifico · ITUniversity of Modena and Reggio Emilia · ITAzienda Sanitaria Unità Locale di Reggio Emilia · ITUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) vaccines can cause transient local and systemic post-vaccination reactions. The aim of this study was to report uveitis and other ocular complications following COVID-19 vaccination. The study included 42 eyes of 34 patients (20 females, 14 males), with a mean age of 49.8 years (range 18-83 years). The cases reported were three herpetic keratitis, two anterior scleritis, five anterior uveitis (AU), three toxoplasma retinochoroiditis, two Vogt-Koyanagi-Harada (VKH) disease reactivations, two pars planitis, two retinal vasculitis, one bilateral panuveitis in new-onset Behçet's disease, three multiple evanescent white dot syndromes (MEWDS), one acute macular neuroretinopathy (AMN), five retinal vein occlusions (RVO), one non-arteritic ischemic optic neuropathy (NAION), three activations of quiescent choroidal neovascularization (CNV) secondary to myopia or uveitis, and one central serous chorioretinopathy (CSCR). Mean time between vaccination and ocular complication onset was 9.4 days (range 1-30 days). Twenty-three cases occurred after Pfizer-BioNTech vaccination (BNT162b2 mRNA), 7 after Oxford-AstraZeneca vaccine (ChAdOx1 nCoV-19), 3 after ModernaTX vaccination (mRNA-1273), and 1 after Janssen Johnson & Johnson vaccine (Ad26.COV2). Uveitis and other ocular complications may develop after the administration of COVID-19 vaccine.

Indexed as

COVID-19ocular complicationsSARS-CoV-2 diseaseuveitisvaccinationvaccinevaccine-associated uveitis

Identifiers

PMID34945256
PMCPMC8704915
OpenAlexW4200608310

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.