Evidence map›Paper›PMID 34945222›Full record

ArticleJournal of clinical medicine2021

The Uncertain Benefit of Adjuvant Chemotherapy in Advanced Low-Grade Serous Ovarian Cancer and the Pivotal Role of Surgical Cytoreduction.

Racheal Louise Johnson, Alexandros Laios, David Jackson, David Nugent, Nicolas Michel Orsi, Georgios Theophilou, Amudha Thangavelu, Diederick de Jong

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Racheal Louise JohnsonESGO Center of Excellence in Advanced Ovarian Cancer Surgery, Department of Gynaecological Oncology, St. James's University Hospital, Leeds LS9 7TF, UK.ORCID 0000-0002-2677-2709
Alexandros LaiosESGO Center of Excellence in Advanced Ovarian Cancer Surgery, Department of Gynaecological Oncology, St. James's University Hospital, Leeds LS9 7TF, UK.ORCID 0000-0002-4870-7393
David JacksonDepartment of Medical Oncology, St. James's University Hospital, Leeds LS9 7TF, UK.
David NugentESGO Center of Excellence in Advanced Ovarian Cancer Surgery, Department of Gynaecological Oncology, St. James's University Hospital, Leeds LS9 7TF, UK.
Nicolas Michel OrsiLeeds Institute of Medical Research, St. James's University Hospital, Leeds LS9 7TF, UK.
Georgios TheophilouESGO Center of Excellence in Advanced Ovarian Cancer Surgery, Department of Gynaecological Oncology, St. James's University Hospital, Leeds LS9 7TF, UK.
Amudha ThangaveluESGO Center of Excellence in Advanced Ovarian Cancer Surgery, Department of Gynaecological Oncology, St. James's University Hospital, Leeds LS9 7TF, UK.
Diederick de JongESGO Center of Excellence in Advanced Ovarian Cancer Surgery, Department of Gynaecological Oncology, St. James's University Hospital, Leeds LS9 7TF, UK.ORCID 0000-0003-0081-674X
St James's University Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In our center, adjuvant chemotherapy is routinely offered in high-grade serous ovarian cancer (HGSOC) patients but less commonly as a standard treatment in low-grade serous ovarian cancer (LGSOC) patients. This study evaluates the efficacy of this paradigm by analysing survival outcomes and by comparing the influence of different clinical and surgical characteristics between women with advanced LGSOC (

Indexed as

cytoreductionhigh-grade serous ovarian cancer (HGSOC)low-grade serous ovarian cancer (LGSOC)surgical complexitysurvival

Identifiers

PMID34945222
PMCPMC8704009
OpenAlexW4200538500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.