Evidence map›Paper›PMID 34945175›Full record

ArticleJournal of clinical medicine2021

Sentinel Lymph Node Biopsy vs. Observation in Thin Melanoma: A Multicenter Propensity Score Matching Study.

Antonio Tejera-Vaquerizo, Aram Boada, Simone Ribero, Susana Puig, Sabela Paradela, David Moreno-Ramírez, Javier Cañueto, Blanca de Unamuno-Bustos, Ana Brinca, Miguel A Descalzo-Gallego and 26 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Sentinel Lymph Node Biopsy in Melanoma: Overview and Updates.International journal of molecular sciences · 2025
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors at 13 institutions in 3 countries.

Antonio Tejera-VaquerizoDermatology Department, Instituto Dermatológico GlobalDerm, 14700 Palma del Río, Spain.
Aram BoadaDermatology Department, Hospital Universitari Germans Trials i Pujol, Institut d'Investigació Germans Trias i Pujol, Universitat Autònoma de Barcelona, 08916 Badalona, Spain.ORCID 0000-0001-9809-5308
Simone RiberoMedical Sciences Department, Section of Dermatology, University of Turin, 10124 Turin, Italy.
Susana PuigMelanoma Unit, Dermatology Department, Hospital Clinic, Universitat de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.ORCID 0000-0003-1337-9745
Sabela ParadelaDepartamento de Dermatología, Hospital Universitario de la Coruña, 15006 La Coruña, Spain.
David Moreno-RamírezMelanoma Unit, Medical-&-Surgical Dermatology Department, Hospital Universitario Virgen Macarena, 41009 Sevilla, Spain.
Javier CañuetoDermatology Department, Complejo Asistencial Universitario de Salamanca, 37007 Salamanca, Spain.
Blanca de Unamuno-BustosDermatology Department, Hospital Universitario La Fe, 46126 Valencia, Spain.
Ana BrincaDepartament of Dermatology, University Hospital of Coimbra, 3000-075 Coimbra, Portugal.
Miguel A Descalzo-GallegoUnidad de Investigación, Fundación Piel Sana, Academia Española de Dermatología, 28008 Madrid, Spain.
Simona Osella-AbateMedical Sciences Department, Section of Surgical Pathology, University of Turin, 10124 Turin, Italy.ORCID 0000-0002-9886-7694
Paola CassoniMedical Sciences Department, Section of Surgical Pathology, University of Turin, 10124 Turin, Italy.ORCID 0000-0003-1977-7410
Sebastian PodlipnikMelanoma Unit, Dermatology Department, Hospital Clinic, Universitat de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.ORCID 0000-0003-4150-0522
Cristina CarreraMelanoma Unit, Dermatology Department, Hospital Clinic, Universitat de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.ORCID 0000-0003-1608-8820
Sergi Vidal-SicartNuclear Medicine Department, Hospital Clinic Barcelona, Universitat de Barcelona, Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.ORCID 0000-0002-6303-3606
Ramón PigemMelanoma Unit, Dermatology Department, Hospital Clinic, Universitat de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.
Agustí TollMelanoma Unit, Dermatology Department, Hospital Clinic, Universitat de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.
Ramón RullSurgery Department, Hospital Clinic, Universidad de Barcelona, 08036 Barcelona, Spain.
Llucìa AlosPathology Department, Hospital Clinic, Universidad de Barcelona, 08036 Barcelona, Spain.ORCID 0000-0002-3460-0384
Celia RequenaDermatology Department, Instituto Valenciano de Oncología, 46009 Valencia, Spain.
Isidro BolumarSurgery Department, Instituto Valenciano de Oncología, 46009 Valencia, Spain.
Víctor TravesPathology Department, Instituto Valenciano de Oncología, 46009 Valencia, Spain.
Ángel PlaOtorhinolaringology Department, Instituto Valenciano de Oncología, 46009 Valencia, Spain.
Almudena Fernández-OrlandMelanoma Unit, Medical-&-Surgical Dermatology Department, Hospital Universitario Virgen Macarena, 41009 Sevilla, Spain.
Ane JakaDermatology Department, Hospital Universitari Germans Trials i Pujol, Institut d'Investigació Germans Trias i Pujol, Universitat Autònoma de Barcelona, 08916 Badalona, Spain.ORCID 0000-0003-2699-1159
María Teresa Fernández-FiguerasPathology Department, Hospital Universitari Germans Trial i Pujol, 08916 Badalona, Spain.ORCID 0000-0002-2366-7110
Nina Anika RicharzDermatology Department, Hospital Universitari Germans Trials i Pujol, Institut d'Investigació Germans Trias i Pujol, Universitat Autònoma de Barcelona, 08916 Badalona, Spain.ORCID 0000-0003-0027-8769
Ricardo VieiraDepartament of Dermatology, University Hospital of Coimbra, 3000-075 Coimbra, Portugal.
Rafael Botella-EstradaDermatology Department, Hospital Universitario La Fe, 46126 Valencia, Spain.
Concepción Román-CurtoDermatology Department, Complejo Asistencial Universitario de Salamanca, 37007 Salamanca, Spain.
Lara Ferrándiz-PulidoMelanoma Unit, Medical-&-Surgical Dermatology Department, Hospital Universitario Virgen Macarena, 41009 Sevilla, Spain.
Nicolás Iglesias-PenaDepartamento de Dermatología, Hospital Universitario de la Coruña, 15006 La Coruña, Spain.ORCID 0000-0002-7282-5015
Carlos FerrándizDermatology Department, Hospital Universitari Germans Trials i Pujol, Institut d'Investigació Germans Trias i Pujol, Universitat Autònoma de Barcelona, 08916 Badalona, Spain.ORCID 0000-0001-9030-8399
Josep MalvehyMelanoma Unit, Dermatology Department, Hospital Clinic, Universitat de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.
Pietro QuaglinoMedical Sciences Department, Section of Dermatology, University of Turin, 10124 Turin, Italy.
Eduardo NagoreDermatology Department, Instituto Valenciano de Oncología, 46009 Valencia, Spain.ORCID 0000-0003-3433-8707
Instituto de Salud Carlos III · ESFundación Instituto Valenciano de Oncología · ESUniversitat Autònoma de Barcelona · ESUniversity of Turin · ITHospital Universitario Virgen Macarena · ESComplejo Hospitalario de Salamanca · ESComplexo Hospitalario Universitario A Coruña · ESHospital Clínic de Barcelona · ESHospital Universitari i Politècnic La Fe · ESUniversity of Coimbra · PTConsorci Institut D'Investigacions Biomediques August Pi I Sunyer · ESHospital Universitari Germans Trias i Pujol · ESSpanish Academy of Dermatology and Venereology · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The therapeutic value of sentinel lymph node biopsy (SLNB) in thin melanoma remains controversial. The aim of this study is to determine the role of SLNB in the survival of thin melanomas (≤1 mm). A multicenter retrospective observational study was designed. A propensity score matching was performed to compare patients who underwent SLNB vs. observation. A multivariate Cox regression was used. A total of 1438 patients were matched by propensity score. There were no significant differences in melanoma-specific survival (MSS) between the SLNB and observation groups. Predictors of MSS in the multivariate model were age, tumor thickness, ulceration, and interferon treatment. Results were similar for disease-free survival and overall survival. The 5- and 10-year MSS rates for SLN-negative and -positive patients were 98.5% vs. 77.3% (

Indexed as

melanomasentinel lymph node biopsysurvival

Identifiers

PMID34945175
PMCPMC8708109
OpenAlexW4200233928

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.