Evidence map›Paper›PMID 34945164›Full record

ArticleJournal of clinical medicine2021

The Expression of Prolactin Receptors in Benign Breast Tumors Is Not Associated with Serum Prolactin Level.

Olena Kolomiiets, Oleksandr Yazykov, Artem Piddubnyi, Mykola Lyndin, Ivan Lukavenko, Volodymyr Andryushchenko, Anatolii Romaniuk, Roman Moskalenko

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 74% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Olena KolomiietsDepartment of Pathology, Sumy State University, 40022 Sumy, Ukraine.
Oleksandr YazykovPrivate Clinic "MRIYA", 40004 Sumy, Ukraine.
Artem PiddubnyiDepartment of Pathology, Sumy State University, 40022 Sumy, Ukraine.ORCID 0000-0002-6508-0131
Mykola LyndinDepartment of Pathology, Sumy State University, 40022 Sumy, Ukraine.
Ivan LukavenkoPrivate Clinic "MRIYA", 40004 Sumy, Ukraine.
Volodymyr AndryushchenkoPrivate Clinic "MRIYA", 40004 Sumy, Ukraine.
Anatolii RomaniukDepartment of Pathology, Sumy State University, 40022 Sumy, Ukraine.
Roman MoskalenkoDepartment of Pathology, Sumy State University, 40022 Sumy, Ukraine.ORCID 0000-0002-2342-0337
Sumy State University · UA

Funding

Ministry of Education and Science of Ukraine 0118U003570
6 · The paper itself

Abstract

The role of prolactin (PRL) and its receptors in the initiation and development of benign breast tumors (BBT) has not been sufficiently studied. An imbalance in the system of hormone homeostasis is crucial in the development of BBT. In particular, an association between elevated prolactin levels and the development of BBT has been reported. Our study showed no significant differences between PRL receptor (PRL-R) expression in BBT tissue under normal and elevated serum PRL levels. There was also no significant correlation between age, PRL-R expression in BBT tissue, intact tissue, and PRL level in the serum. There was a strong significant correlation (

Indexed as

benign breast tumorsprolactinprolactin receptors

Identifiers

PMID34945164
PMCPMC8705851
OpenAlexW4200600479

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.