Evidence map›Paper›PMID 34945162›Full record

ArticleJournal of clinical medicine2021

Change in Viral Load during Antiviral Therapy Is Not Useful for the Prediction of Hearing Dysfunction in Symptomatic Congenital Cytomegalovirus Infection.

Takumi Kido, Yuki Kyono, Shutaro Suga, Ruka Nakasone, Shinya Abe, Mariko Ashina, Hisayuki Matsumoto, Kenji Tanimura, Kandai Nozu, Kazumichi Fujioka

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Takumi KidoDepartment of Pediatrics, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Yuki KyonoDepartment of Pediatrics, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Shutaro SugaDepartment of Pediatrics, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Ruka NakasoneDepartment of Pediatrics, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Shinya AbeDepartment of Pediatrics, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Mariko AshinaDepartment of Pediatrics, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Hisayuki MatsumotoDepartment of Clinical Laboratory, Kobe University Hospital, Kobe 650-0017, Japan.
Kenji TanimuraDepartment of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Kandai NozuDepartment of Pediatrics, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.ORCID 0000-0002-0290-3137
Kazumichi FujiokaDepartment of Pediatrics, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.ORCID 0000-0002-9913-6447
Kobe University · JPKobe University Hospital · JP

Funding

grants-in-aid from the Ministry of Health, Labour and Welfare of Japan H23-Jisedai-Ippan-001, H25-Jisedai-Shitei-003, and H30-Kansei-Shitei-002the Japan Agency for Medical Research and Development, AMED JP15gk0110003, JP16gk0110021, and JP18gk0110021h0003, JP19gk0110037s0201, and JP20gk0110037s0502
6 · The paper itself

Abstract

For symptomatic congenital cytomegalovirus infections (CCMVI), the usefulness of changes in viral load during valganciclovir (VGCV) treatment for the prediction of hearing dysfunction (HD) is unclear. To determine the utility of viral load change in the whole blood or urine for the prediction of HD, we performed a retrospective study to compare viral load changes during VGCV treatment between CCMVI infants with (

Indexed as

antiviral therapycongenital cytomegalovirus infectionhearing dysfunctionviral load

Identifiers

PMID34945162
PMCPMC8709202
OpenAlexW4200524927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.