ArticleJournal of clinical medicine2021
Mismatch Negativity and P3a Impairment through Different Phases of Schizophrenia and Their Association with Real-Life Functioning.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Detecting electrophysiological alterations in psychiatric disorders through event-related microstates: a systematic review.Frontiers in psychiatry · 2025Pooled it
- Biomarkers for Predicting Clinical Deterioration in Schizophrenia-Spectrum Disorders: A Systematic Review.Brain sciences · 2026Review
- Audiovisual speech perception deficits in unaffected siblings of children with developmental language disorder.Brain and language · 2025Article
- Early Auditory Temporal Processing Deficit in Children with Autism Spectrum Disorder: The Research Domain Criteria Framework.Brain sciences · 2024Article
- Clarifying directional dependence among measures of early auditory processing and cognition in schizophrenia: leveraging Gaussian graphical models and Bayesian networks.Psychological medicine · 2024Article
- P300 in schizophrenia: Then and now.Biological psychology · 2024Review
- External validation of the five domains of negative symptoms: Focus on cognition, functional capacity, and real-world functioning.European psychiatry : the journal of the Association of European Psychiatrists · 2023Article
- A multivariate approach to investigate the associations of electrophysiological indices with schizophrenia clinical and functional outcome.European psychiatry : the journal of the Association of European Psychiatrists · 2023Article
- Application of Machine Learning to Diagnostics of Schizophrenia Patients Based on Event-Related Potentials.Diagnostics (Basel, Switzerland) · 2023Article
- Unveiling the Associations between EEG Indices and Cognitive Deficits in Schizophrenia-Spectrum Disorders: A Systematic Review.Diagnostics (Basel, Switzerland) · 2022Review
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18 authors.
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Abstract
Impairment in functioning since the onset of psychosis and further deterioration over time is a key aspect of subjects with schizophrenia (SCZ). Mismatch negativity (MMN) and P3a, indices of early attention processing that are often impaired in schizophrenia, might represent optimal electrophysiological candidate biomarkers of illness progression and poor outcome. However, contrasting findings are reported about the relationships between MMN-P3a and functioning. The study aimed to investigate in SCZ the influence of illness duration on MMN-P3a and the relationship of MMN-P3a with functioning. Pitch (p) and duration (d) MMN-P3a were investigated in 117 SCZ and 61 healthy controls (HCs). SCZ were divided into four illness duration groups: ≤ 5, 6 to 13, 14 to 18, and 19 to 32 years. p-MMN and d-MMN amplitude was reduced in SCZ compared to HCs, independently from illness duration, psychopathology, and neurocognitive deficits. p-MMN reduction was associated with lower "Work skills". The p-P3a amplitude was reduced in the SCZ group with longest illness duration compared to HCs. No relationship between P3a and functioning was found. Our results suggested that MMN amplitude reduction might represent a biomarker of poor functioning in SCZ.
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